Degrees of Health

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Have We Been Wrong About Sunlight? | Pelle Lindqvist

Wed, 25 Mar 2026 00:00:00 GMT

Is sunlight really as harmful as we’ve been told?

In this episode, Pelle Lindqvist explores the nuanced science of sun exposure, challenging conventional narratives around skin cancer and health.

We discuss:

Sunlight and all-cause mortality
The role of vitamin D and nitric oxide
Why location and skin type matter
Sun exposure vs modern public health advice
The difference between overexposure and avoidance

This is a conversation about rethinking sunlight, not as something to fear, but something to better understand.

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Mental Health, Ketosis & The Metabolic Brain | Dr. Erin Bellamy

Wed, 18 Mar 2026 00:00:00 GMT

In this episode, I sit down with Dr. Erin Bellamy to explore one of the most important and overlooked topics in modern health.. the connection between metabolic health and mental health.

We discuss how ketones may impact the brain, why nutritional ketosis can create a sense of calm and resilience, and how ketogenic therapy is being used in cases ranging from anxiety and depression to bipolar disorder and schizophrenia.

Dr. Bellamy also shares real patient case studies, her own journey from psychology and NHS work into metabolic psychiatry, and the most common mistakes people make when trying ketogenic therapy on their own.

We cover:

how ketosis feels subjectively
ketones, anxiety and emotional “buffer space”
metabolic psychiatry and mitochondrial health
bipolar disorder, schizophrenia, depression and PTSD
therapeutic ketosis vs weight-loss keto
electrolytes, keto flu and common mistakes
ketone tracking, GKI and exogenous ketones
why food may be one of the most powerful tools in mental health

A fascinating conversation on the future of mental health treatment.

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Is deuterium one of the most overlooked variables in cancer and metabolism? | Gábor Somlyai

Wed, 11 Mar 2026 00:00:00 GMT

In this episode, Ben speaks with Gábor Somlyai, one of the earliest researchers to investigate the role of deuterium depletion in cancer biology.

Gábor argues that while mainstream oncology has focused heavily on genes, mutations, and targeted drugs, a deeper regulatory layer may have been missed: the ratio between deuterium and hydrogen inside the body. He explains why he believes this matters for cell division, mitochondrial function, metabolic health, and cancer progression.

The conversation covers the origins of his research, the early experiments that convinced him deuterium was influencing cell growth, and why he believes deuterium depletion should one day become part of standard oncology care.

They also explore:

why deuterium may matter at a sub-molecular level
how mitochondria produce deuterium-depleted metabolic water
the possible connection between ketogenic metabolism and lower deuterium states
why deuterium depleted water has become such a focus of his work
how he thinks about relapse prevention and long-term metabolic health
the potential implications beyond cancer, including diabetes, aging, and cognition

Whether you agree with the framework or are hearing about deuterium for the first time, this is a fascinating conversation about scientific paradigms, unconventional ideas, and the possibility that one missing variable could change how we think about disease.

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Cancer as a Metabolic Disease - Insulin, Keto, and Recurrence | Dr. Kristy Kessling

Wed, 04 Mar 2026 00:00:00 GMT

What if cancer isn’t primarily a genetic disease but a metabolic one?

In this episode, Ben sits down with radiation oncologist Dr. Kristy Kessling to explore a radically different lens on cancer, one that centers on mitochondria, insulin resistance, inflammation, and the internal “terrain” of the body.

Dr. Kessling explains why she believes cancer begins with mitochondrial stress not random bad luck and why insulin and IGF-1 may be more important drivers than most patients are ever told. We unpack the difference between attacking cancer cells and improving the body’s metabolic environment, and why those two approaches are not the same.

Topics covered:

Why “cancer is a metabolic disease” is more than just a slogan
The role of insulin, IGF-1, and glucose in tumour growth
BRCA genes: why genes are not destiny
The three biomarkers Dr. Kessling prioritizes for prevention and recurrence
Ketogenic and carnivore diets, what matters, and common mistakes
Fasting and ketosis alongside chemotherapy (and why some patients experience fewer side effects)
Cancer stem cells and the importance of terrain
Why recurrence prevention mirrors prevention itself
The overlooked role of stress, mindset, and emotional health

This conversation challenges the conventional narrative and offers something deeply empowering the idea that metabolic health gives us more agency than we’ve been led to believe.

Whether you’re navigating a diagnosis, focused on prevention, or simply interested in the intersection of metabolism and chronic disease, this episode offers a hopeful and thought-provoking perspective.

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Breathing and Metabolism: Unraveling the Connection | Dr Jonathan Jun

Wed, 25 Feb 2026 00:00:00 GMT

This episode is a deep dive into physiology, sleep science, and the hidden systems shaping how we breathe.

We cover:

Why your body is basically a walking engine producing CO₂

The real mechanism behind sleep apnea

Why two people with the same BMI can have totally different breathing

How body fat distribution affects airway function

The surprising connection between ketosis and breathing improvements

The study showing ketogenic diets improved CO₂ clearance in certain patients

Whether exogenous ketones could affect sleep and breathing

Why sleep science is still full of mysteries doctors can’t yet explain

Dr. Jun also shares what research he’d run if he had unlimited funding — and the answer could change how we treat respiratory disorders.

If you’re interested in sleep, metabolism, health optimization, or physiology, this conversation will change how you think about breathing.

👍 Subscribe for more expert conversations on health, performance, and human biology.

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Secure Love Is Built, Not Found | Julie Menanno

Wed, 18 Feb 2026 00:00:00 GMT

Couples therapist and Secure Love author Julie Menanno joins Ben Hopkins to unpack what actually creates secure love and why most couples try to create change in the exact wrong way.

Julie explains why validation and emotional safety open the nervous system to growth, how to “accept the person but not the behavior,” and what anxious, avoidant, and disorganized attachment can look like in real relationships.

We talk about:

Why anxious attachment can chase highs and comebacks
Why avoidant attachment fears failure and shuts down
Disorganized attachment: unpredictability, overwhelm, and dissociation
How couples learn emotional skills in the moment
What secure love feels like: calm, connection, and repair

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The Hidden Role of Light in Health, Cancer & Metabolism | Dr Max Gulhane

Wed, 11 Feb 2026 00:00:00 GMT

Are we beings of light — literally?

In this episode, Ben Hopkins is joined by Dr. Max Gulhane to unpack the science of biophotons, mitochondria, circadian rhythm, and sunlight — and how light may be a core driver of metabolism, cancer risk, and chronic disease.

From quantum biology to sun exposure myths, grounding, vitamin D, and ancestry-specific health, this conversation challenges modern public health narratives and asks a deeper question:

What if disease isn’t just biochemical — but a light mismatch?

A fascinating deep dive into the intersection of biology, evolution, and modern illness.

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Are You Tired but Wired? Productive but Exhausted? | Jessica Turton

Wed, 04 Feb 2026 00:00:00 GMT

In this episode, Ben Hopkins is joined by dietitian Dr Jessica Turton to explore why chronic under eating may be one of the most overlooked causes of fatigue, brain fog, poor sleep and stubborn health issues.

We break down how eating too little increases stress hormones, disrupts metabolism, drives nutrient deficiencies, and creates “fake energy” that keeps high performers running on empty.

Ben also shares his personal experiment with eating more and why it led to better sleep, clearer thinking, and major improvements in strength and recovery.

A must listen if you’re eating “healthy” but still feel awful.

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Oral Health as an Early Warning Sign of Metabolic Disease | Sarah Hancock

Wed, 28 Jan 2026 00:00:00 GMT

Is tooth decay an early warning sign of metabolic disease?

In this episode, I’m joined by Dr. Sarah Hancock to explore a connection most of us were never taught the powerful link between oral health, nutrition, and long term metabolic health.

Dental caries (tooth decay) is the most common diet related disease in the world yet it’s rarely discussed as part of chronic disease prevention. Sarah explains how frequent consumption of refined carbohydrates, nutrient poor diets, and early childhood eating patterns can affect not just our teeth, but our metabolism, insulin sensitivity, and future disease risk.

We cover:

Why cavities may be an early metabolic red flag
How diet impacts teeth beyond brushing and fluoride
The link between refined carbs, insulin resistance, and oral health
Why poor oral health often begins in childhood
How nutrient dense diets may protect both teeth and metabolism

This conversation reframes oral health as a whole body issue, not just a dental one.

🎙️ Listen now and share with anyone interested in preventative health.

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Is Cancer Really a Metabolic Disease or an Infection? | Mark Lintern

Wed, 21 Jan 2026 00:00:00 GMT

In this episode, Ben sits down with Mark Lintern to challenge that assumption and explore a radically different idea...

What if cancer is a disease of suppression, not failure?

Drawing on the metabolic theory, the Warburg effect, mitochondrial biology, and emerging research into the tumour microbiome, Mark lays out a compelling framework that reframes cancer as a chronic cell danger response potentially driven by persistent infection.

They unpack..

Why the metabolic theory explains more than genetics but still leaves gaps.

Why apoptosis and immune evasion don’t fully fit the “broken cell” narrative.

How mitochondria may intentionally suppress oxidative phosphorylation.

Why prostate cancer breaks the Warburg rule entirely.

The role of fungi, bacteria, and the tumour associated microbiome.

Why immunotherapy often fails and sometimes backfires.

How infection biology may explain inflammation, immune suppression, and tumour growth.

What this means for real world treatment strategies, from metabolic therapy to repurposed drugs.

This is a deep, systems-level conversation. Not about silver bullets but about first principles.

If theory informs treatment, then getting the theory right matters.

We cover:

🧬 Metabolic vs somatic mutation theory

🔥 The Warburg effect as a defensive response

🦠 Infection, fungi, and the tumour microbiome

🧠 The cell danger response model

🫁 Oxygen, mitochondria, and immune signalling

🧪 Prostate cancer as a metabolic outlier

💊 Repurposed drugs, antifungals, and metabolic therapies

🌱 Why cancer may be adaptive — not defective

This episode isn’t about certainty.

It’s about asking better questions.

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GLP-1s, Testosterone & the New Health Paradigm | James O’Hara

Wed, 14 Jan 2026 00:00:00 GMT

Health optimisation isn’t about chasing trends. It’s about understanding trade-offs, context and biology. In this episode, Ben Hopkins is joined by James O’Hara to explore what really lies beneath today’s biggest health conversations, from GLP-1 drugs and testosterone decline to peptides, diet, recovery, and ageing.

Drawing on personal experience and emerging research, they unpack why population data doesn’t always translate to individual outcomes, how modern lifestyles are quietly eroding hormonal health, and where new tools may help or harm, if misunderstood.

From anabolic recovery and muscle retention to carnivore diets, light therapy and mental resilience, this is a wide-ranging conversation for anyone trying to navigate health in an increasingly complex world.

We cover:

💉 GLP-1 agonists, weight loss & metabolic trade-offs

🧠 Testosterone decline, ageing & lifestyle factors

💪 Anabolic recovery, peptides & injury repair

🥩 Carnivore diets, hormones & long-term health

⚡ Light therapy, inflammation & healing

🧬 Emerging research shaping modern wellness

It’s nuanced, honest and grounded in real-world experience, not just theory.

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Fructose, Fat, and the Future of Metabolic Health | Dr Richard Johnson, MD

Wed, 07 Jan 2026 00:00:00 GMT

Obesity isn’t just about willpower. It’s biology and it’s been hacked. In this episode, Dr. Richard Johnson (Professor of Medicine at the University of Colorado) joins Ben to explain why your body still thinks it's living in the wild and how the same survival switch that once kept us alive may now be quietly driving obesity, diabetes, dementia and addiction.

From fructose and uric acid to GLP-1s, Alzheimer's, and mitochondrial health, this conversation unpacks the hidden biology shaping how we store fat, crave sugar and so often lose control with it.

We cover:

🧠 Fructose, the brain & Alzheimer’s

🧪 The survival switch that drives obesity

🍷 Why uric acid links sugar and alcohol

💊 GLP-1s, food addiction & metabolic dysfunction

⚡ What carbs do to your mitochondria

It's deep, practical and quite possibly, completely paradigm-shifting.

Find Dr Richard:

Paper on alcohol, fructose, and liver disease

Mentioned in this episode:

Book - Nature Wants Us to Be Fat by Dr. Richard Johnson

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Ketones, Mood, and Mitochondria: The Missing Link in Mental Health | Dr Ana Andreazza

Wed, 17 Dec 2025 08:07:30 GMT

What if the root of mental illness isn’t all in your head but in your cells?

Dr. Ana Andreazza is leading one of the most exciting shifts in psychiatric science: away from neurotransmitters and towards the mighty mitochondria. In this episode, she and Ben explore the metabolic foundations of mood disorders, how lactate and ketones impact the brain and why most psychiatric medications only form part of the picture.

From bipolar disorder and inflammation to mitochondrial transplants and brain organoids, Ana is at the forefront of rethinking how we treat, prevent and understand mental illness.

We cover:

🧬 Why mitochondria might be the missing link in mental illness

🔥 How lactate and inflammation can trigger mania and mood swings

🥦 Why nutrition is still missing from most psychiatric care

⚡ The link between energy metabolism and neurotransmitters

🥼 What mitochondrial transplants could mean for brain health

🥑 The promise of ketones in bipolar and mood regulation

💊 Why we need both meds and metabolic interventions

Find Ana:

More about Ana's work

Papers & Research

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Light, Cancer & Consciousness: Biology Through a New Lens | Dr Nirosha Murugan

Wed, 03 Dec 2025 00:00:00 GMT

Forget everything you thought you knew about biology. Dr Nirosha Murugan takes us way beyond molecules into the world of light, electricity and the energetic language of life itself. Here we explore a radical new lens on human health: one where energy, not just chemistry, drives disease, healing and even consciousness.

From the role of light in cancer and red light therapy, to cells that 'think' without brains, to why homeostasis might be the wrong goal altogether.

We cover:

⚡ Why biology might be better understood as patterns of energy

🧠 “Thinking” organisms that don’t have brains

🌞 How light (even in the womb) shapes our biology

🧬 Reframing cancer through the lens of energy resistance

🧘‍♀️ Bioelectricity, metabolism & the limits of current science

🌀 Consciousness as emergent energy, not brain activity

This episode is a ride - part biology, part physics, part philosophy - and all energy.

Find Nirosha:

X (Twitter)

Mentioned in this episode:

A New Science of Life by Rupert Sheldrake

Demons in the Machine by Paul Davies

Energy and Information in Art, Science, and Technology

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DunedinPACE Test via TrueDiagnostics

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Annie vs. Aging: Atomic Longevity Habits From The Longevity Leaderboard

Wed, 26 Nov 2025 07:33:48 GMT

🧬 What does it take to age slower than more than 99.9% of the population?

Meet Annie who is currently ranked #2 in the Rejuvenation Olympics, measuring the slowest biological aging in the world (second only to Bryan Johnson). But Annie’s not a billionaire with a team of scientists. She’s a self-experimenting New Yorker who figured out what works for her and it’s more simple (and more joyful) than you’d think.

In this episode, Ben and Annie explore her full protocol (yes, including a Kind Bar and red light therapy), the wild (and sometimes worrying) world of longevity culture and how the simplest shifts - walking more, laughing nightly, cutting alcohol - helped Annie feel better and slow her aging to 0.46x the typical rate.

We cover:

🧠 Annie's supplement stack & skin protocol

🥦 How diet impacts pace of aging and why Annie is not anti-meat

🧪 Senolytics, grounding mats, liposomal vitamins & NOVOS

🧨 The supplement that lowered her skin age by 7 years

🧘‍♀️ Why overtraining raised her aging score

📉 What didn’t work: PEMF, metformin & too much “juice”

A refreshingly human conversation in a space that too often forgets what health really means.

Find Annie:

Instagram @annienosh

Mentioned in this episode:

NOVOS Core

Oura Ring

Rejuvenation Olympics leaderboard

Atomic Habits by James Clear

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Why Drew Decker Believes Ketosis Could Change Mental Health Forever

Wed, 29 Oct 2025 00:00:00 GMT

Your brain runs on what you eat. So what happens when you fuel it with fat instead of sugar?

Drew Decker and Ben join together to discuss his study on the ketogenic diet and depression in college students and how a simple dietary shift led to a 70% reduction in depression scores. No tracking apps, no dieticians, no hand-holding, just students with a budget, a plan, and a mission to feel better.

Drew’s journey started after a traumatic brain injury in the military and led him to Dr. Jeff Volek’s lab, where he’s now leading research into how ketosis may impact mental health, PTSD, inflammation, BDNF, energy metabolism and more.

This is one of those episodes that’s equal parts hopeful, data-driven and deeply personal.

🧠 Ketosis as a tool for mental health

📉 The downside of keto? Pretty capped.

🥑 How college students stuck to keto on a tight budget

🧬 BDNF, energy metabolism & brain inflammation

🧠 PTSD, trauma & the future of metabolic psychiatry

💊 Exogenous vs endogenous ketones

🥩 Animal-based, dairy-based, veggie-heavy — what actually matters

📚 The ketogenic diet as metabolic medicine

Find Drew:

Instagram - @drew_d_decker

ResearchGate

Mentioned in this episode:

Keto-Mojo

Feasibility of Ketogenic Diet in College Students with Depression - A pilot study

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Why 'Eat Less, Move More' Doesn’t Work | Jessica Turton, PhD

Tue, 21 Oct 2025 23:00:00 GMT

Most people who end up in Jessica Turton’s health clinic have already tried everything from calorie tracking, low-fat, fasting, moving more, eating less… and still nothing works to shift weight. So what’s going on?

Ben sits down with Jessica - dietitian, nutritionist, researcher - to talk about what happens when your body’s been stuck in energy deficit for years, and how the real issue for many people isn’t overeating, it’s under eating.

They get into why most nutrition advice backfires, how your brain handles hunger, the impact of stress on metabolism and why we need to stop treating weight loss like a willpower problem.

We cover:

🧠 The real metabolic cost of chronic dieting

🥑 Low-carb ≠ low-calorie (and why that matters)

💉 Why type 2 diabetes is reversible if you treat the cause

🔥 Why most people are walking around under-fueled

💊 GLP-1s, binge cycles & the illusion of control

We also look at what low-carb actually looks like when done well, and how to eat more food without losing your mind. Fascinating if you've ever been in this cycle yourself (which is most of us) and how we might actually be able to break the loop.

Find Jessica:

Ellipse Health online clinic

Mentioned in this episode:

The Minnesota Starvation Experiment

Jessica’s PhD Research on Type 1 Diabetes

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Muscles, Cancer & the Future of Exercise Medicine | Professor Mark Febbraio

Tue, 14 Oct 2025 23:00:00 GMT

What if your muscles could talk to your organs and maybe even prevent cancer? Here, Ben sits down with world-renowned exercise scientist Professor Mark Febbraio to dismantle the science behind myokines - molecules released by muscle that signal throughout the body.

Insights covered in this episode:

🧪 Myokines and inter-organ communication

🦠 Exercise’s role in cancer prevention

🧬 Inflammation, cytokines & what IL-6 does

🧠 The cognitive power of exercise & BDNF

🏋️‍♂️ What type of training protects best and how much is too much

💉 Why we don’t understand GLP-1 side effects yet

🧫 The future of exercise mimetics & blood-based therapies

🧠 Why “we don’t know” might be science’s most honest answer

From interleukin-6’s double life to how exercise blood can fight tumours, this one’s a digestible dive into how movement truly is medicine.

Find Mark and papers reference in this episode:

ResearchGate

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Weight Plateaus, GLP-1s & Why Keto Got So Complicated | Amy Berger, MS, CNS

Tue, 07 Oct 2025 23:00:00 GMT

Keto doesn’t have to be complicated. Yep, you heard that right.

Nutritionist and author Amy Berger joins us to unpack the chaos of keto culture and how a once-simple metabolic switch has turned into a jungle of macros, misinformation and food fear. Amy cuts through the noise and brings keto back to what it was always meant to be: a simple, flexible, effective way of eating.

Together with Ben, she covers the realities of weight loss stalls, hormonal shifts, fasting fads, the rise of ultra-processed keto products and what the science says about vegetables, carnivore diets, GLP-1s and calories.

We cover:

🥩 Carnivore vs Keto - what’s happening metabolically

💊 GLP-1s, weight loss drugs & long-term risk

📉 Why weight loss might stall (and what to do about it)

🧃 Keto vs processed “keto” - marketing vs metabolism

🥬 In defense of vegetables (yes, really)

📊 Fasting: myth, magic, or just misunderstood?

Whether you're new to low-carb or neck-deep in macros and metabolic rabbit holes - this one’s for you.

Find Amy:

Mentioned in this episode:

The Alzheimer’s Antidote by Amy Berger

The Stall Slayer by Amy Berger

End Your Carb Confusion by Amy Berger & Dr. Eric Westman

Dr. Eric Westman - Keto researcher & collaborator

The Art and Science of Low Carbohydrate Living - Dr. Jeff Volek & Dr. Stephen Phinney

Eat Like a Human - Dr. Bill Schindler

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Anorexia Recovery, Ketosis & How We Medicalised Hunger | Michelle Ann Hurn, RD

Tue, 30 Sep 2025 23:00:00 GMT

What if we’ve been treating eating disorders the wrong way?

In this deeply personal and provocative episode, registered dietitian Michelle Hurn shares her journey from severe anorexia and psychiatric medication to ultra-running and mental clarity through a radical change in nutrition.

Ben and Michelle unpack the broken foundations of dietetics, why metabolic health is inseparable from mental health and how the standard of care may be making things worse.

We cover:

🥩 Why animal-based diets are helping eating disorder recovery

🧠 The link between stable blood sugar and psychiatric health

📉 The connection between calories, insulin and metabolic disorders

🏃‍♀️ Running long distances with zero carb loading

🧪 Exogenous ketones vs. yerba mate for ketone production

🔥 GLP-1 drugs, health at every size and what we’re getting wrong

From hospital feeding tubes to ketones and carnivore protocols, this is a raw, real and - we hope - hopeful conversation about what happens when you stop following the food pyramid and start listening to your body.

Find Michelle:

The Fox Family Food Fight

X / Twitter

Mentioned in this episode:

Book - The Dietitian’s Dilemma by Michelle Ann Hurn

Case Study: Ketogenic Diets in Anorexia

Paper - Therapeutic Carbohydrate Restriction

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JAMA Psychiatry paper on metabolic dysfunction & mental illness

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“Ketones Work - Even If We Don’t Know Why” | Dr Adrian Soto-Mota, MD, PhD

Tue, 23 Sep 2025 23:00:00 GMT

Dr Adrian Soto-Mota, MD, PhD is one of the clearest and most curious voices in metabolic research and he’s not afraid to say what doesn’t make sense anymore.

Dr Adrian is an internal medicine physician and metabolic researcher based in Mexico City. In this conversation, we go deep on the limitations of RCTs, why calorie logic keeps breaking down, what lean mass hyper-responders teach us about lipids, and why sometimes the data works before we understand the mechanism.

We also talk about the surprising impact of meat-heavy diets on IBD, why exogenous ketones matter more than people think and how metabolic dysfunction might be sitting at the core of psychiatric illness.

This one is full of nuance and yet grounded in clinical reality.

We cover:

🧠 The metabolic demands of the human brain

💊 Why calories don’t predict fat gain the way we think

🧬 Lean mass hyper-responders and cholesterol interpretation

📉 Why nutritional RCTs can’t answer what we want them to

🧪 Hormones, definitions and broken language in medicine

🧘‍♂️ Metabolic psychiatry & the case for new mental health models

Find Adrian:

X profile

Google scholar

Mentioned in this episode:

Modeling Life by Alan Garfinkel

Bernoulli’s Fallacy by Aubrey Clayton

Rethinking Statistics by Richard McElreath

Human Metabolism by Keith Frayn & Rhys Evans

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The Dopamine Trap - Why We Keep Scrolling & How to Stop | Michael Long

Tue, 16 Sep 2025 23:00:00 GMT

📲 Why do we keep chasing things that never quite satisfy?

We’re joined by The Molecule of More co-author Michael E. Long to unpack dopamine and why our brains are wired to want more, not to enjoy what we already have.

From doomscrolling to dating apps, productivity obsessions to endless self-improvement, we explore how dopamine fuels craving and not contentment, and what we can do to stop living in the next and start living in the now. Michael shares insights from his new book, Taming the Molecule of More, and explains how understanding this one molecule could help us reclaim joy, focus, relationships, and maybe even our sanity.

We cover:

❤️ Dopamine in dating, sex and long-term love

📉 Why chasing ‘more’ always gives you less

🛍️ Behavioral addiction and craving cycles

📚 The difference between thinking about your life vs being in your life

📈 Practical tools to tame the dopamine system

This episode is for anyone interested in behavioural science, addiction, relationships or anyone who just wants to feel a little less hijacked by their phone.

Find Michael:

themoleculeofmore.com

Taming the Molecule of More

Books: The Molecule of More

Mentioned in this episode:

A History of Western Philosophy by Bertrand Russell

The World According to Garp by John Irving

The Braverman Test

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The Case Against Plants | Dr Anthony Chaffee

Tue, 09 Sep 2025 23:00:00 GMT

Some people find health through green smoothies. Others find it in 3 kilos of steak cooked in ghee.

Dr. Anthony Chaffee is a neurosurgical registrar and ex-professional rugby player who’s been running on nothing but animal products for years. No salads. No supplements. No exceptions. In this conversation, we get into the weeds of his theory, that many modern illnesses (autoimmune conditions, metabolic disorders, mental health struggles) are not mysterious at all, they are the result of eating the wrong fuel.

🥩 Why plants aren’t as innocent as they look

🧬 Autoimmunity, inflammation & symptom reversals

🍳 What a carnivore diet looks like day-to-day

📉 Why most nutrition advice is upside down

📚 The history of meat-based medicine (it’s older than you think)

🧠 What brain fog, bloating, and back pain have in common

Take a listen as he lays out the logic, science and experience behind a radical return to meat and see if it changes your perspective.

Find Dr Anthony:

Mentioned in this episode:

The Relation of Alimentation and Disease by Dr James Salisbury

Strong Medicine by Dr Blake Donaldson

Nutrition and Physical Degeneration by Dr Weston Price

Bruce Ames research on naturally occurring plant carcinogens

JAMA (2016) Sugar industry’s influence on dietary fat recommendations

Dr. Paul Saladino

Dr. Shawn Baker

Thomas Seyfried (cancer metabolism)

Dr. Dominic D’Agostino (ketosis & therapeutic diets)

Exploring the benefits of red and infra light therapy? Our community receive 10% off via this link

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-Barry Brenner's 1982 paper

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The Hormone That Could Reverse Kidney Disease | Thomas Weimbs, PhD

Tue, 02 Sep 2025 23:00:00 GMT

'High-protein diets hurt your kidneys!'. 'Once kidney disease starts, it only gets worse'. Heard something similar? It's just not the whole picture and also showing to be quite far from the truth.

Dr Thomas Weimbs, PhD is a Professor of Bioengineering at UCSB where his lab has spent over 20 years studying chronic kidney disease. What they found, mostly by accident like all great science, changed the course of their research entirely. From mouse models to human trials, they discovered that a state of nutritional ketosis could not only slow but potentially reverse the progression of kidney disease and all without drugs.

We cover:

🧠 Why the real cause of most kidney disease is metabolic

🥩 High-protein diets, carbs and the Barry Brenner myth

🧪 The surprising effects of ketosis on kidney function

🧂 Uric acid crystals and pH - the overlooked trigger

🔬 BHB (ketones) as hormones - and what they actually do

⚡ Why no one makes money from metabolic health (and why that matters)

This episode is about kidneys, their function and dysfunction. But it's also about what happens when we follow the science, even when it contradicts the textbooks.

Mentioned in this episode:

-Effects of a continuous remote care intervention including nutritional ketosis on kidney function and inflammation in adults with type 2 diabetes

- “Weimbs Lab” on Facebook - patient-led community

Find Thomas Weimbs:

Research

Santa Barbara Nutrients - KetoCitra

Weimbs Lab - UCSC

Exploring the benefits of red and infra light therapy? Our community receive 10% off via this link

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Cancer Is Personal: Treat It That Way | Ben Whately & Padman Vamadevan

Tue, 05 Aug 2025 23:00:00 GMT

Cancer treatment isn’t one disease = one drug. It’s thousands of different stories playing out at a molecular level and yet when it comes to care, we’re still treating most of them the same way.

Padman Vamadevan and Ben Whately, co-founders of Astron Health, are rethinking oncology from the ground up. Here we explore why recurrence is such an under-addressed problem, how AI can help oncologists cut through a tidal wave of research and what it looks like to track cancer like a chronic disease instead of a binary cure-or-palliative model.

We cover:

🧬 Why two 'identical' cancers can be worlds apart biologically

🤖 How AI condenses 170,000+ research papers into actionable options

🩺 The blank space after an 'all clear' and how to fill it

📊 Longitudinal data: tracking disease drivers over time

🛠️ Safe iteration with proven drugs, supplements & lifestyle changes

Find Astron Health:

Astron Health Website

Mentioned in this episode:

Book - Tripping Over the Truth by Travis Christofferson

Exploring the benefits of red and infra light therapy? Our community receive 10% off via this link

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The Secret Role of Water in Health | Gerald Pollock

Tue, 08 Jul 2025 23:00:00 GMT

What if everything we learned about water was missing its most important piece?

In this episode, we speak with Professor Gerald Pollack - biomedical scientist, professor, and author of The Fourth Phase of Water - whose research reveals a side of water that’s been hiding in plain sight. From how cells create energy to what actually drives chronic disease, this conversation turns biology inside out - but stays rooted in how this changes our view of the practical day to day.

Pollack’s ideas challenge convention. But they also unlock new ways to understand hydration, mitochondria, cancer, grounding, and even the link between consciousness and health.

💧 Why 'hydration' is so much more than drinking water

⚡ EZ (Exclusion Zone) water - the battery inside your cells

🔬 Mitochondria, light, energy and the missing link in cellular health

🎯 Cancer, chronic disease & the role of intracellular dehydration

🧠 How grounding + infrared work - electrically

🧪 Rejected science and the cost of going against the grain

📚 Transmutation: can living beings create elements?

This episode is big. And yes, we go there. Let us know your thoughts - we love hearing from you!

Find Gerald:

Exploring the benefits of red and infra light therapy? Our community receive 10% off via this link: ⬇️

https://rechargehealthas.sjv.io/DyJ3mn

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Women Aren’t Broken. We’re Misinformed. | Food, Hormones and Healing with Dr Pauline Cox, MSc

Tue, 01 Jul 2025 23:00:00 GMT

Most of us were never taught what hormones actually do. We just noticed things getting weird - heavier periods, brain fog, random mood swings that made us question our entire personality.

And when we asked for help, we got vague answers. A prescription. Maybe a “come back in 6 months.”

That’s why we sat down with Pauline Cox, a functional nutritionist who’s actually good at explaining this stuff. She's worked with hundreds of women dealing with endometriosis, PCOS, low thyroid, fatigue, and all the “you’re fine” symptoms that so many of us learn to live with.

This episode is about finally understanding what’s going on and how much control we do actually have here. Through food, light, movement, supplements… but also, through knowing what to look for, and what to question.

🧠 The gut-hormone connection (it’s not all in your head)

🥗 Food choices that support your cycle

🩸 Endometriosis and why it’s often misunderstood

💡 Oestrogen, thyroid, and the subtle signs we miss

📉 What chronic inflammation does to your mood

⚠️ When tracking your health makes you feel worse

🧪 The supplements Pauline comes back to again and again

This is one for every woman - and for anyone who loves one.

Let us know what hits home. We’re always listening!

Find Pauline:

Sow and Arrow - Health Store and Education Platform

Mentioned in this episode:

Books - Hungry Woman: Eating for good health, happiness and hormones + Primal Living in a Modern World

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“How I Dropped My Biological Age by 20 Years" Part 2 | Michael Lustgarten, PhD

Tue, 24 Jun 2025 23:00:00 GMT

PART 2! If you missed it, we highly recommend checking out Part 1 before listening to this episode.

We all age. But what if we could slow it down, reshape it, or even pause it altogether?

After connecting over one of our most viewed episodes with Dr. Glen Jefferys, we got to hear from scientist and relentlessly curious longevity researcher Dr. Michael Lustgarten. He’s been tracking over 50 biomarkers for nearly a decade and has reduced his biological age by more than 20 years.

In this episode, we explore what that process looks like for Michael with data. Lots of data.

We cover:

🧪 How to interpret and act on blood markers

🔁 Supplement cycles, blood work feedback & knowing when to stop

🧬 Hormones, hypothyroidism, and adjusting thyroid meds over time

🧠 SHBG, testosterone & why 'high' isn’t always better

☀️ The underestimated power of light, sleep, and rhythm

🧊 Would he freeze himself? Yes - and here’s why

🔮 What consciousness might teach us about aging

This episode is a goldmine for listeners who are already tracking labs, looking for more advanced interpretation strategies, trying to refine their own protocols and avoid over-supplementation or 'stack overload'.

Find Michael:

Academic Publications

Mentioned in this episode:

The 120-Year Diet by Dr Roy Walford

The Alchemist by Paulo Coelho

Dr. Morgan Levine’s PhenoAge Biological Age Test

Kurt JaiMungal’s Theories of Everything

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“How I Dropped My Biological Age by 20 Years" Part 1 | Michael Lustgarten, PhD

Tue, 24 Jun 2025 23:00:00 GMT

We all age. But what if we could slow it down, reshape it, or even pause it altogether?

In this episode, we explore what that process looks like for Michael with data. Lots of data.

We cover:

🧪 How to interpret and act on blood markers

🔁 Supplement cycles, blood work feedback & knowing when to stop

🧬 Hormones, hypothyroidism, and adjusting thyroid meds over time

🧠 SHBG, testosterone & why 'high' isn’t always better

☀️ The underestimated power of light, sleep, and rhythm

🧊 Would he freeze himself? Yes - and here’s why

🔮 What consciousness might teach us about aging

Find Michael:

Academic Publications

Mentioned in this episode:

The 120-Year Diet by Dr Roy Walford

The Alchemist by Paulo Coelho

Dr. Morgan Levine’s PhenoAge Biological Age Test

Kurt JaiMungal’s Theories of Everything

Want to watch this on video? Subscribe on YouTube

Instagram @degreesofhealth

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You’re Not Tired - You’re Undercharged: Red Light and Real Energy | Bjørn Ekeberg, PhD

Tue, 17 Jun 2025 23:00:00 GMT

We talk a lot about nutrition, movement, and sleep when it comes to health. But there's a missing piece in most conversations: light.

In this episode, we sit down with Bjørn Ekeberg - philosopher of science turned founder of Recharge Health - to explore how red and near-infrared light can support recovery, improve energy, and help us reconnect with our biology.

We unpack what red light therapy is, how mitochondria drive everything from mood to metabolism, and why so many of us are unknowingly light-deficient. Athletes, health nerds, or if you're just tired of being tired - listen up. The conversation about energy, tech, and how we support the body’s natural intelligence.

We cover:

🔴 What red & near-infrared light do

⚡️ Mitochondria, energy and light deficiency

🧠 Cognitive function & mental clarity

🏃‍♂️ Muscle recovery, inflammation, and pain

🧬 Why movement isn't enough without light

🚦 Safe, at-home red light therapy

If we promote something, we want to ensure it is genuinely something we a) trust in and b) use. This is no exception. The FlexBeam from Recharge Health is what Ben and I (producer Eloise) genuinely use for our own fix of red and infrared light. It is health-tech designed for real life. If you're exploring red light therapy, the team has offered our community 10% off via this link: ⬇️

https://rechargehealthas.sjv.io/DyJ3mn

(this helps support the podcast and the conversations we’re building.) Let us know if you end up going for one - we're not sure there's a part of our body that hasn't reaped benefits from it.

Find Bjørn/Red Light Devices:

Recharge Health or on instagram

NIR effects on mitochondria and VO2 Max

Mentioned in this episode:

Study - Infrared Low-Level Laser Therapy (Photobiomodulation Therapy) before Intense Progressive Running Test of High-Level Soccer Players

Substance: The Material World and the Making of the Modern Mind by Nick Hawkes

Bjørn’s academic work in cosmology and the philosophy of science. His book - Metaphysical Experiments: Physics and the Invention of the Universe

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Water Is a Battery - Are You Charging Yours? | Sara Pugh, PhD

Tue, 10 Jun 2025 23:00:00 GMT

We know health isn't just about the food you eat or the supplements you take. But do we really understand the other elements that are so crucial - the light we see, the water we drink, and even the way we think?

Sara Pugh, PhD, Quantum Biologist and Ketogenic Coach shares how she has brought together physics and wellness. She explains why light and water are key players in how our bodies works and how simple daily choices can make a huge difference to our overall health and wellbeing.

We cover:

💧 How water in your body acts like a battery

🧬 Mitochondria, movement and real energy

🌞 Daily light routines to set your body clock

🧠 Hypnosis, consciousness, and the power of belief

📵 The hidden impact of EMFs and blue light

🌍 Small changes that can make a big difference

This episode is for anyone curious about how to align modern life with the natural rhythms we evolved for - and why it matters so much now.

Find Sara:

Mentioned in this episode:

Gerald Pollock’s 4th Phase of Water

The Invisible Rainbow by Arthur Firstenberg

Dan Winter’s Golden Ratio & Coherence

Rupert Sheldrake’s Morphic Fields

Reality Is Plastic by Anthony Jacquin

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The Hidden Health Risks of 5G | Olle Johansson PhD

Tue, 03 Jun 2025 23:00:00 GMT

This one’s for anyone who’s ever wondered: Are we really safe in a wireless world?

What if the invisible forces all around us - your phone, your Wi-Fi, even your toothbrush - were quietly shaping your health and the planet’s health too?

In this conversation, EMF researcher Olle Johansson shares his decades of experience researching the health impacts of electromagnetic fields - the kind you can’t see but you might well be feeling. From rising chronic diseases to the decline of natural pollinators, Olle connects the dots between our modern tech-filled lives and the health of every living thing. He also shares why insurance companies won’t touch EMF risks, why screen dermatitis is on the rise, and - crucially - what we can do right now to protect ourselves.

We cover:

📡 The hidden health impacts of EMFs

🧬 Why Wi-Fi, Bluetooth & cell phones matter

🧒 Why kids might be at higher risk

🐝 What happens to bees & bugs (and why it matters)

🌿 How to live with tech - without losing your mind (or your health)

🤝 Why human connection matters more than ever

Find Olle:

Email - olle.johansson500@gmail.com

Material submitted to UK parliament on EMF and 5G

Mentioned in this episode:

Polarization and Biological Activity: Study analyzing the role of polarization in EMFs and their biological effects

Immune System Disturbance: Research on how EMFs can disturb immune function, leading to potential health risks

Electrohypersensitivity Recognition: Discussion on Sweden's recognition of electrohypersensitivity as a functional impairment

Myelin Damage from RF-EMFs: Review of evidence linking radiofrequency EMF exposure to myelin damage and electrohypersensitivity

WHO Classification: The World Health Organization's classification of certain EMFs as possible carcinogens

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You Don’t Need Millions to Slow Aging | Julie Gibson Clark

Tue, 27 May 2025 23:00:00 GMT

What happens when your body completely crashes and you have no energy to get off the couch?

For Julie Gibson Clark, that moment became the turning point. After being diagnosed with heavy metal poisoning, she began a journey that would transform not only her health, but how she thinks about aging, wellness, and self-discipline taking her to the leaderboard of the Rejuvenation Olympics worldwide (a public leaderboard ranking biological aging via epigenetic clocks), and currently ageing at only 65 days per 100 days. Julie shares her accessible approach to longevity - blending science, intuition, and a healthy dose of self-compassion. From structured routines and strength training to intuitive fasting, oxalates, supplements, and spiritual rituals, Julie unpacks the systems she uses to feel younger, stronger, and more grounded.

This is a conversation about real-life longevity - without $10k-a-month protocols or lab coats. Just honesty, experimentation, and a deep respect for beauty and balance.

We cover:

🧬 Heavy metal poisoning
🥗 The menu - 100g protein and 1lb of veggies
💪 Why strength training is a longevity foundation
🔄 Using fasting-mimicking diets to reset & recover
🧠 The “inner general” vs. self-compassion - when to push, when to rest
🧪 How to experiment with your own protocol (without perfectionism)

This is longevity, lived.

Find Julie:

Mentioned in this episode:

Book - The Longevity Diet by Valter Longo

Book - Lifespan by David Sinclair

Book - The Complete Guide to Fasting by Jason Fung

NOVOS Core supplement - longevity blend

Rejuvenation Olympics

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Study - Persistent epigenetic differences associated with prenatal exposure to famine in humans

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Dr Nicole Cain | From Panic to Peace: Rewire An Anxious Nervous System

Tue, 20 May 2025 23:00:00 GMT

If you've ever felt like your anxiety was swallowing you whole - like something was broken inside but like you have to suck it up and get on with it anyway - you've got to know you don't have to stay there, and this episode might help to see how.

In discussion here with leading expert in trauma-informed clinical psychology and holistic medicine for anxiety and panic, Dr Nicole Cain unpacks with us that anxiety isn’t the problem - yep, that's right. It's not the problem - it’s the signal. Through her personal and clinical journey, she reframes anxiety as the body’s way of showing us where healing needs to happen - that anxiety isn’t something to be silenced, but something to be understood.

We explore anxiety through the lens of neuroplasticity, mitochondrial health, and trauma-informed healing and Dr. Cain shares her 4-step process for rewiring your nervous system, explains how anxiety manifests differently in each of us and reveals why addressing the root cause is the only real path we have to emotional well-being.

We cover:

🧠 Why anxiety is the body’s call for healing - not a disorder

🌪️ How trauma shapes adult patterns

🧘‍♀️ A 4-step method to stop panic in its tracks

🧬 The link between mitochondria, energy & mental health

🧪 Natural tools that work: Chamomile, Kava, L-theanine & more

🧠 Neuroplasticity and the power to rewire your brain

This isn’t about quick fixes or suppression. It’s about healing at the root, meeting your anxiety with curiosity, and walking with it to support us in becoming panic-proof, present, and free.

Find Dr Nicole Cain:

Mentioned in this episode:

Study - Adverse Childhood Experiences (ACEs) Study

Paper - Ideology and the Canadian health care system

Quiz - Take the 9 Types of Anxiety Quiz - find out how your anxiety manifests (e.g. gut-based, chest-based, thought-based, etc). This helps tailor the best response to your physiological presentation.

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Instagram @degreesofhealth

Study - Carbohydrate Restriction-Induced Elevations in LDL-Cholesterol and Atherosclerosis: The KETO Trial

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Dr Philip Ovadia | Cholesterol Isn’t the Enemy: Reversing Heart Disease Through Metabolic Health

Mon, 12 May 2025 23:00:00 GMT

Here, heart surgeon Dr Philip Ovadia dismantles decades of medical dogma around cholesterol and heart disease. Once morbidly obese and pre-diabetic, Dr Ovadia shares his transformation and exposes why the traditional cholesterol-focused approach to heart health is failing millions.

He speaks about the real root causes - insulin resistance, metabolic dysfunction, and inflammation - and explains why diet, not drugs, is the key to long-term health. This conversation is a roadmap to reclaiming your health and staying off the operating table.

We cover:

🫀 Why cholesterol isn’t the root cause of heart disease

🧬 The role of insulin resistance & inflammation in heart health

🥩 Keto vs. Carnivore - what’s the difference, and who are they for?

💊 The truth about statins and PCSK9 inhibitors

🧠 How metabolic health connects to brain, hormone & immune function

🔥 Reversing heart disease & taking control of your own health

Find Dr Philip Ovadia:

Instagram / YouTube

Website - services for U.S. and international patients focused on reversing metabolic disease

Mentioned in this episode:

Book - Stay Off My Operating Table by Dr Philip Ovadia

Book - Why We Get Sick by Dr. Benjamin Bikman

Book - Good Calories, Bad Calories + The Case Against Sugar by Gary Taubes

Documentary - Cholesterol Code (releasing soon)

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Dr Dan Turner, PhD | The Enhanced Games - Performance Enhancement Done Safely and Legally

Tue, 29 Apr 2025 23:00:00 GMT

Join us for an exploration of high-stakes innovation and athlete health, and learn how we might just be scratching the surface of what’s possible in the world of elite performance.

Here we’re sitting down with Dr. Dan Turner, PhD, Director of Athletic Safety at the Enhanced Games, where athletes push the boundaries of human potential with performance-enhancing substances — under medical supervision. Dan, also a Lead Scientist for High Performance at Red Bull, is a leading expert in high-performance health and athlete safety, shares his pioneering work with the Enhanced Games and reveals how the use of substances like anabolic steroids, metabolic modulators, and even gene editing could reshape the future of athletics. With athlete health and fairness at the core, this conversation digs into the ethics of performance enhancement, the importance of sleep and recovery, and the science behind metabolic boosters.

We cover:

🧬 The Enhanced Games: A new arena for athletic competition with performance-enhancing substances

💉 Medical Supervision: The importance of safe use, avoiding misuse, and ensuring long-term health through comprehensive monitoring.

🛏️ Sleep: The ultimate performance-enhancing tool

⚡ Rad Framework: Readiness, Emotional Efficiency, and Durability - a strategic approach to mastering high performance

🧪 Innovative Substances: How metabolic modulators, botanicals, and even CRISPR technology could be the next frontier in sports.

🧠 Mindset & Performance: Coaching high performers - overcoming mental blind spots, stress management, and building resilience.

From the Enhanced Games’ mission to level the playing field to the future of human performance through genetic innovations, this conversation offers a glimpse into where sports and health optimisation are headed. It’s not just about competing harder - it’s about competing smarter.

Find Dan:

Enhanced Games

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Scott Walker | Life Lessons from a Kidnap Negotiator - Knowing What People Really Want

Wed, 23 Apr 2025 20:21:14 GMT

What do crisis negotiations, hostage rescues, and your everyday conversations have in common? More than you think.

Former Scotland Yard detective, military intelligence operator, and globally recognised negotiation expert Scott Walker offers a masterclass in the art of influence, communication, and emotional self-regulation. Scott shares the tools he’s developed through decades of real-world experience - techniques that help us stay calm under pressure, navigate conflict with confidence, and bring more agency into how we show up in our life. These principles have been honed with elite teams under the most intense, high-stakes situations - this isn’t just about negotiation - it’s about living intentionally, leading with humility, and learning to choose your response, no matter what’s happening around you.

We cover:

🧠 The power of emotional regulation - pause, reset, choose

🎯 Preparation for conversation - what are the 5 most likely challenges? And how will you handle them?

🧍‍♂️ Agency - taking part in your own rescue, not outsourcing responsibility

💬 Conversation types - do you want to be helped, heard or hugged?

🤝 Empathy & influence - how to genuinely understand someone else before making your point

🪞 Biases, blindspots & humility - how status and identity shape conflict

🔁 Everyday negotiation - because we’re all in conversations with purpose

No esoteric, abstract theory here - it's a practical deep dive into how we can use communication as a tool for resolution, for growth, for leadership, and for health.

Find Scott:

Course - Thrive Under Pressure

Book - Order Out Of Chaos

Book - Eye of the Storm - Scott Walker. Available for Pre-Order, Release 20th May 2025.

Mentioned in this episode:

Book - The Wisdom of Psychopaths by Kevin Dutton

Book - Supercommunicators by Charles Duhigg

Book - Taken on Trust by Terry Waite

Book - Man’s Search for Meaning by Victor Frankl

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Instagram @degreesofhealth

Paper The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer

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Dr Tomás Duraj | Part 2 Can You Starve Cancer? | Mitochondria, Ketones & The New Metabolic Playbook

Thu, 17 Apr 2025 23:00:00 GMT

In Part 1, we laid the foundation for a new understanding of cancer - one that begins with mitochondrial dysfunction and the bioenergetic breakdown of cells. In Part 2, we move into the real-world implications: how we treat, manage, and potentially prevent cancer using a metabolic lens.

Dr. Tomás Duraj explores the emerging tools and protocols being studied - from ketogenic metabolic therapies to glutamine inhibition, and how combining dietary strategies with systemic approaches might redefine cancer care completely. It is not throwing away what we already know, but rather using what we know works and disregarding what doesn’t.

We also look at the failures of past trials, why so many therapies underperform, and what happens when the patient shifts from passive recipient to active participant in their treatment.

In Part 2, we cover:

🥑 The difference between dietary and pharmacological ketogenic therapy

📉 Why traditional cancer treatment starts backwards - and what to consider instead

📊 GKI (Glucose Ketone Index) as a key metabolic marker

⚙️ Using fasting, exercise, and ketones to shift cellular metabolism

🧬 How patient-led protocols could shape future cancer trials

🧠 The potential of metabolism-based priming for immunotherapy success

⏱️ Why time, compliance, and education are critical variables in success

This episode isn’t just about understanding cancer - it’s about reimagining how we treat it, measure it, and empower patients to become collaborators in their own care.

Mentioned in this episode:

Publications

Book - Tripping Over The Truth by Travis Christofferson

Paper - Successful application of dietary ketogenic metabolic therapy in patients with glioblastoma

Find Dr Duraj:

Ketogenic Metabolic Therapy Forum

Dr Seyfried’s lab at Boston College

Donate to the lab

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Instagram @degreesofhealth

Paper The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer

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Dr Tomás Duraj | Part 1 Targeting Cancer Metabolism - Why Mitochondria Matter More Than Mutations

Wed, 16 Apr 2025 05:53:36 GMT

We’ve been told for decades that cancer is a genetic disease - a matter of unlucky mutations. But what if we’ve been starting in the wrong place?

In this two-part episode, medical doctor and cancer metabolism researcher Dr. Tomás Duraj takes us through a paradigm-shifting look at cancer - exploring the metabolic theory, how it contrasts with the prevailing somatic mutation theory, and why mitochondrial dysfunction may hold the key to both treatment and prevention.

This episode covers the history of cancer theory, the evolutionary biology behind it, and why current models might be missing the mark by focusing on downstream symptoms instead of upstream causes.

In Part 1, we cover:

🧬 The somatic mutation theory vs. the metabolic theory of cancer🧠 Why mitochondria may be the origin, not a side-effect📚 The history of cancer theory - and why we got stuck on genetics🧪 Redefining the Warburg effect and oxidative phosphorylation🧬 BRCA mutations, mitochondrial signalling & inherited risk⚡ Energy before all else - how bioenergetics impacts everything🍽️ Why dietary interventions (like ketogenic therapy) are still so misunderstood

This conversation is foundational - if you want to understand why cancer research has been stalling (and where the future might be), this is where to start and end.

🎙️ Stay tuned for Part 2, where Dr Tomás dives into the potential of metabolic therapies in real-life application and treatment frameworks.

Mentioned in this episode:

Publications

Book - Tripping Over The Truth by Travis Christofferson

Paper - Successful application of dietary ketogenic metabolic therapy in patients with glioblastoma

Find Dr Duraj:

Ketogenic Metabolic Therapy Forum

Dr Seyfried’s lab at Boston College

Donate to the lab

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Instagram @degreesofhealth

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Dr Rob Kominiarek | Hormones, Health, Longevity - Fix Your Lifestyle First, Hormones Will Follow

Tue, 08 Apr 2025 23:00:00 GMT

Hormones are often misunderstood or oversimplified (because they are quite complicated). But according to Dr. Rob Kominiarek, they are one of the most powerful (and most overlooked) levers we have for health, vitality, and aging well. So it's worth knowing what we can do to improve them and feel better, right?

In his practice, Dr Rob Kominiarek focuses on individualised, root-cause approaches towards hormone balance, metabolic health, and long-term wellness. Yes he uses all the tools in the box, but only when they're necessary and fit the client. Here, Dr Rob and Ben are exploring the role of testosterone in men and women, how hormone imbalances manifest differently in men and women, and why lab results alone aren’t the full picture.

We cover:

💥 Symptom over numbers - why how you feel matters more than your lab results

💊 Cellular resistance and over-prescribed TRT - when your body makes hormones, but they don’t do what they’re supposed to

🧘‍♀️ Women’s hormones - why birth control and low protein intake create a "perfect metabolic storm"

💥 Peptides & personalised protocols - tools for healing and hormone regulation without cookie-cutter plans

🥗 How lifestyle affects hormones - under-eating, overtraining, birth control, and stress

⚡ Symptoms vs. Lab Results - why chasing "optimal T levels" is a distraction if you’re not solving the root issue

🚫 The real danger? Focusing on visible muscle while ignoring bone loss, energy decline, and mood shifts

This episode also endeavours to bring more information to the fore on female hormones, and where there are distinct differences between the two sexes that are critical to our understanding and optimisation of sex hormones. More to come on this!

Find Dr. Rob:

Renue Health

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Stephanie Seneff, PhD | MIT Scientist Warns: This Chemical is Everywhere (And It's Dangerous)

Tue, 01 Apr 2025 23:00:00 GMT

We hear about toxins in our food all the time - but what if one chemical was quietly linked to the rise of so many chronic conditions and diseases? Autism, Alzheimer’s, diabetes, fatty liver disease, Parkinson’s, ADHD, even certain cancers?

Meet Dr. Stephanie Seneff, an MIT scientist who has spent years uncovering the shocking effects of glyphosate - the active ingredient in the world’s most commonly used weedkiller. Stephanie explains how this one component could be the root behind the biggest health crises of our time - and in this episode, she breaks down exactly how.

We cover:

🔥 The rise of glyphosate - where it came from & how it took over our food supply

🦠 How it disrupts your gut, microbiome, and nutrient absorption

💧 Deuterium - the “heavy hydrogen” affecting mitochondria & metabolism

🥑 How a low-deuterium diet (ketogenic, high-fat) may help reverse damage

❌ Why Ozempic ultimately won't work full cycle

💉 Glyphosate in vaccines

🌍 AI & the future of medicine

Dr. Seneff’s research is controversial but the evidence is mounting. Could glyphosate be the silent spring of our time?

Find Stephanie:

Blocking the Increase of Intracellular Deuterium Concentration Prevents the Expression of Cancer-Related Genes, Tumor Development, and Tumor Recurrence in Cancer Patients

Research Papers

Mentioned in this episode:

Book: Toxic Legacy

The Effect of Glyphosate on Human Sperm Motility and Sperm DNA Fragmentation

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Instagram @degreesofhealth

The NAD+/PARP1/SIRT1 Axis in Aging

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Daniel Lewis | Part 2: Reversing Aging (Without Billionaire Budgets)

Wed, 26 Mar 2025 00:00:00 GMT

Part 2.

We all know the headlines: billionaire-funded biohacking, flashy protocols, impossible routines. But what if longevity could be simpler - accessible, structured, and something you can actually integrate into real life?

Meet Daniel Lewis: lawyer by day, longevity guinea pig by night, and formerly #1 in the Rejuvenation Olympics. Daniel isn’t chasing immortality with an unlimited budget - he’s focused on what works, what’s measurable, and what fits into a normal life.

In this episode, Daniel shares exactly how he’s slowed his rate of ageing to just 0.62 - and dropped his telomere age from 27 to 18 (he's 35) - all while working full time.

We cover:

🧬 What really ages us - telomeres, epigenetics, and the hallmarks of aging explained

🏋️ Exercise without overcomplication - strength training, Zone 2 cardio, and chasing a 6-minute mile

💤 Sleep & recovery - micro-dosing melatonin, glycine and white noise

💊 Supplements based on research - spermidine, NAD precursors, alpha-ketoglutarate, and green tea extract (ECGC)

⚖️ Balance, not obsession - treats, travelling, and a cocktails

✨ The future of aging - cellular reprogramming, genetic testing, and what’s next in the longevity space

Daniel’s approach is refreshingly doable - it’s science-backed, data-informed, and built to work around real life. No extremes. Just process.

🔗 Find Daniel:

Instagram: @daniellewis4life

Rejuvenation Olympics

Mentioned in this episode:

Animal study - Long-term treatment with spermidine increases health span of middle-aged Sprague-Dawley male rats

loncevity.org - protocol updates & insights

Want to watch this on video? Subscribe on YouTube

Instagram @degreesofhealth

The NAD+/PARP1/SIRT1 Axis in Aging

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Daniel Lewis | Part 1: Reversing Aging (Without Billionaire Budgets)

Wed, 26 Mar 2025 00:00:00 GMT

Part 1.

In this episode, Daniel shares exactly how he’s slowed his rate of ageing to just 0.62 - and dropped his telomere age from 27 to 18 (he's 35) - all while working full time.

We cover:

🧬 What really ages us - telomeres, epigenetics, and the hallmarks of aging explained

🏋️ Exercise without overcomplication - strength training, Zone 2 cardio, and chasing a 6-minute mile

💤 Sleep & recovery - micro-dosing melatonin, glycine and white noise

💊 Supplements based on research - spermidine, NAD precursors, alpha-ketoglutarate, and green tea extract (ECGC)

⚖️ Balance, not obsession - treats, travelling, and a cocktails

✨ The future of aging - cellular reprogramming, genetic testing, and what’s next in the longevity space

Daniel’s approach is refreshingly doable - it’s science-backed, data-informed, and built to work around real life. No extremes. Just process.

🔗 Find Daniel:

Instagram: @daniellewis4life

Rejuvenation Olympics

Mentioned in this episode:

Animal study - Long-term treatment with spermidine increases health span of middle-aged Sprague-Dawley male rats

loncevity.org - protocol updates & insights

Want to watch this on video? Subscribe on YouTube

Instagram @degreesofhealth

Effect of forest bathing trips on human immune function

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Dr Melissa Sundermann | Take A Simple Idea - And Take It Seriously.

Wed, 19 Mar 2025 00:00:00 GMT

Can it be this simple?

Simply? Yes.

Dr. Melissa Sundermann ('Doctor Outdoors') - lifestyle medicine physician - shares how six pillars (plus one extra weapon) can prevent, treat, and even reverse chronic disease - no fancy gadgets or prescriptions needed. Melissa's message is pivoted on the fact that our genes are not our destiny - if you disagree, read on. If you agree, hi, we like you, agent of your own health 👋

We cover:

🥗 Food as Medicine - your gut, brain, and mood are all connected

🏋️‍♀️ Movement That Matters - walking 10,000 steps cuts dementia risk by 50%

💤 Sleep & Brain Health - how sleep "cleans" the brain and supports creativity & memory

🚫 Risky Substances - why there’s no safe threshold for alcohol (and other habits to rethink)

🧘 Stress Management - the power of easy, accessible mindfulness tools

👥 The Power of Social Connection - loneliness and isolation: just as risky as smoking

🌳 Nature as Medicine - the science of forest bathing, phytoncides, and why trees may outperform pharmaceuticals

🎯 Her message? The simple ideas, pursued with consistency, are the real “cheat codes” to lifelong vitality.

Find Dr Melissa:

Instragam - @thedoctoroutdoors @motivatormelissa

Linktree

Mentioned in this episode:

Effects of forest environment (Forest bathing) on health promotion and disease prevention

Age-associated chronic diseases require age-old medicine

Dr Tracy Gapin, M.D. | Low Testosterone: Symptoms, Causes & Solutions

Wed, 12 Mar 2025 00:00:00 GMT

🚨 Testosterone is Dropping – Should We Be Worried? 🚨

Testosterone levels have been plummeting for decades with studies showing a 40-50% drop in free testosterone over the last 20-30 years. But why is this happening? And more importantly - what can men do about it?

Dr. Tracy Gapin, urologist and leading expert in men’s health and performance, unpacks the modern testosterone crisis, the role of environmental toxins, lifestyle, and nutrition, and how small daily decisions may be the key to reclaiming long-term health.

We cover:

⚠️ Hidden Symptoms of low T - do any sound familiar to you?

🧪 Endocrine Disruptors - how plastics, chemicals, and even deodorant may be affecting hormones

🏋️ Strength Training & Hormones - boosting T naturally

🥩 Diet & Hormones - the impact of (stressful) low-carb diets, fasting, and caloric restriction on T levels

💉 Peptides - the growing interest in hormone-supporting peptides for recovery, energy & longevity

🧬 Aging as optional? - how to maintain healthspan & vitality for decades

Dr. Gapin emphasises that tiny daily choices - from what we eat to what we put on our skin - can either support or sabotage our hormones. It’s not about perfection, but about building momentum with the right tiny habits.

Find Dr Tracy Gapin:

Website - get a copy of his book for free, the high performance handbook, and a science-based peptide guide.

Atrazine induces complete feminization and chemical castration in male African clawed frogs

Mentioned in this episode:

Age, Disease, and Changing Sex Hormone Levels in Middle-Aged Men

Temporal trends in sperm count

Testosterone deficiency and cardiovascular mortality

The Effect of Testosterone on CV Disease and CV Risk Factors in Men

Role of Testosterone in the Treatment of CV Disease

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Instagram @degreesofhealth

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Lucas Aoun | Unpacking the Testosterone Toolbox - Supplements, Microplastics & Performance

Wed, 26 Feb 2025 00:00:00 GMT

Lads, is your:

energy low?

sex drive fading?

motivation struggling?

You’re not alone.

Testosterone levels are dropping at an alarming rate worldwide - but it’s not just about age. Factors like microplastics, stress, poor sleep, and diet are wreaking havoc on our hormones.

But before jumping on TRT, there are powerful lifestyle and supplement-based interventions that can naturally optimise your testosterone and send it sky rocketing once again. We're chatting here with Lucas Aoun, Australia’s leading biohacker and founder of Boost Your Biology, to unpack:

💡 The real reasons mens T levels are crashing

❌ Why many jump on TRT too soon (and the smarter alternatives)

🧊 The wild science of testicle icing (yes, take that pack of peas on the road)

🌿 The ultimate natural testosterone stacks

🧠 Cutting-edge nootropics, brain hacks, confidence and libido

We talk tons of supplements too including catuaba, pine pollen, shilajit, boron, methylene blue, taurine, cistanche, magnesium, zinc, tonkat ali, stinging nettle root. Plenty to get stuck into if you're looking to up your T!

(Plus a gruelling assault bike challenge to test your limits).

Find Lucas:

Boost Your Biology

Mentioned in this episode:

https://nisupplements.com/

Catuapure Supplement

https://trtfree.com/ - where to find protocols and the supplements Lucas mentions here

Want to watch this on video? Subscribe on YouTube

Instagram @degreesofhealth

Alzheimer’s Disease - What If There Was A Cure?

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Dr Mary Newport | Part 2: Fat, Cholesterol & Metabolic Mayhem: What We Thought We Knew

Wed, 12 Feb 2025 07:05:52 GMT

Part 2 of 2.

For years, fat has been the villain of the food world. We’ve been told it clogs arteries, sends cholesterol through the roof, and leads to heart disease. But is that actually true? It's about time to give fat a fair trial.

Enter Dr Mary Newport. Here, we're discussing Mary's new article (released this month - Feb 2025) analysing 26 studies conducted from 1985 to 2024 with 984 complete datasets - looking specifically at the coconut oil on lipid parameters (total, LDL, HDL cholesterol, and triglycerides).

Mary helps us to break down the history of the lipid-heart hypothesis (aka: the idea that fat = heart disease), the fact this remains what it states (a hypothesis) and yet our entire food belief system is built from it, what the research actually says, and why things are not be as black and white as fat=bad=avoid.

🔍 We cover:

✅ The Fat Fear Factor - where did the idea that fat is bad even come from?

✅ Coconut Oil & Cholesterol - should we be worried to incorporate more coconut/MCT/olive oil on a keto diet? 🥥

✅ Cholesterol 101 - is LDL really the “bad guy,” or is there more to the story?

✅ Metabolism & Health - how things like inflammation and blood sugar fit into the picture

✅ Fuel for Thought - why Mary is a big proponent of MCT oil for brain health

Tune in for a research-backed conversation about fat, cholesterol, keto, and heart health and whether we really have any reason to be side-eyeing that extra few servings of olive oil.

The article in discussion:

Analysis of 26 Studies of the Impact of Coconut Oil on Lipid Parameters: Beyond Total and LDL Cholesterol

Find Mary:

Website (also find here how to get started with a ketogenic diet)

Books by Mary:

Clearly Keto

The Complete Book of Ketones

The Coconut Oil & Low-Carb Solution

Find our previous episode with Mary specifically on use of Coconut Oil for Cognitive Function/Decline Prevention - Mary Newport, M.D. | Brain Fuel: How Coconut Oil and MCTs Can Transform the Alzheimer's Brain

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Instagram @degreesofhealth

Alzheimer’s Disease - What If There Was A Cure?

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Dr Mary Newport | Part 1: Fat, Cholesterol & Metabolic Mayhem: What We Thought We Knew

Wed, 12 Feb 2025 07:04:22 GMT

Part 1 of 2.

🔍 We cover:

✅ The Fat Fear Factor - where did the idea that fat is bad even come from?

✅ Coconut Oil & Cholesterol - should we be worried to incorporate more coconut/MCT/olive oil on a keto diet? 🥥

✅ Cholesterol 101 - is LDL really the “bad guy,” or is there more to the story?

✅ Metabolism & Health - how things like inflammation and blood sugar fit into the picture

✅ Fuel for Thought - why Mary is a big proponent of MCT oil for brain health

Tune in for a research-backed conversation about fat, cholesterol, keto, and heart health and whether we really have any reason to be side-eyeing that extra few servings of olive oil.

The article in discussion:

Analysis of 26 Studies of the Impact of Coconut Oil on Lipid Parameters: Beyond Total and LDL Cholesterol

Find Mary:

Website (also find here how to get started with a ketogenic diet)

Books by Mary:

Clearly Keto

The Complete Book of Ketones

The Coconut Oil & Low-Carb Solution

Want to watch this on video? Subscribe on YouTube

Instagram @degreesofhealth

Hosted on Acast. See acast.com/privacy for more information.

Dr Marianne Brandon, PhD | Why We’re Having Less Sex - The Latest Scoop on Intimacy, Desire and Tech

Wed, 29 Jan 2025 00:00:00 GMT

Has desire for your partner changed within the course of your relationship? Do you feel like you and your partner are mis-matched in terms of desire? Are you curious to know what you could do differently to change this from a sex therapist with over 27 years experience? Read on.

Dr Marianne Brandon, PhD, joins us as we delve into the complex world of sexual dynamics, relationships, and the future of intimacy. As a clinical psychologist, sex therapist, and futurist, Dr. Brandon sheds light on the often-unspoken challenges couples face in long-term relationships, offering fresh perspectives rooted in evolutionary psychology and modern-day realities.

We cover:

👩‍❤️‍👨 Men and Women - why our sexual wiring is fundamentally different and why understanding this matters

🔥 Hijack Your Biology - tapping into primal instincts in safe, trusting relationships

📉 Why Desire Fades - the evolutionary reasons long-term relationships kill lust and tips on how to bring it back

🤖 Sex Tech & VR Porn - how cutting-edge technology is both enhancing and complicating modern relationships

Dr Marianne says - we can’t solve a problem we don’t understand. This episode helps us understand our evolutionary instincts and just how much they play into our modern lives at, largely, an unconscious level - and rather than trying to suppress, ignore, or repress them, to accept them, give them air time, and an outlet.

Find Dr Marianne:

Female Genital Arousal: A Focus on How Rather than Why

Podcast - The Sex Doctors

Blog - The Future of Intimacy, Psychology Today

Marianne's Books

Mentioned in this episode:

Effects of virtual reality erotica on ejaculate quality of sperm donors

The Anxious Generation by Jonathan Haidt

Want to watch this on video? Subscribe on YouTube

Instagram @degreesofhealth

Antioxidants prevent health-promoting effects of physical exercise in humans

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Dr Mark Tarnopolsky, MD, PhD | Mitochondrial Mastery: Supplements, Exercise & Longevity Insights

Wed, 22 Jan 2025 00:00:00 GMT

Dr. Mark Tarnopolsky is a world-renowned expert in mitochondrial health, muscle function, and ageing science. As a clinician-scientist at McMaster University, he has dedicated his career to understanding how we can optimise our mitochondria - the tiny powerhouses in our cells - for better energy, performance, and longevity.

This is for you if you’ve ever asked yourself: Why does energy fade as I age? How can I boost my endurance, strength, and resilience whatever age I am? And what are the best ways to support (even enhance) these powerhouses naturally?

We cover:

🔥 Mitochondria 101 - why they’re central to health, ageing, and energy production

🌟 Signs of mitochondrial dysfunction - fatigue, muscle loss, and cataracts

🏋️‍♀️ Exercise for mitochondria – Endurance vs. resistance training benefits (on mitochondrial mass and function)

💡 Mitochondrial Biogenesis - how to double your mitochondria in 3 months

🍎 Supplements demystified - the science on CoQ10, NAD precursors, beetroot extract, and urolithin A

🧠 Aging & oxidative stress - mitophagy and why antioxidants alone won’t cut it

🩺 Mark’s regimen - he practices what he preaches: the nutrition, supplements, and exercise strategies he uses to stay on top of his game (and hold a +68 VO2 max in his 60s)

What we do know? There’s no shortcut to better mitochondria. What we can do? We listen and we learn what Dr Mark describes to be the gold standard for optimising energy, longevity, and quality of life. Lace up your sneakers, team!

Find Dr Mark:

McMaster University

Supplement Brand - Stay Above Nutrition

Mark’s papers

Mentioned in this episode:

PubMed

Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity

A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men

Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health

Want to watch this on video? Subscribe on YouTube

Instagram @degreesofhealth

Book: https://thelightdoctor.com/

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Dr Martin Moore-Ede | Why Your Health Hinges on the Light You See

Wed, 15 Jan 2025 00:00:00 GMT

The light we see is as crucial as the food we eat, the water we drink, and the air we breathe. Former Harvard Medical School professor and 40-year leading expert in circadian clocks and human health, Dr. Moore-Ede speaks on why our health hinges on getting the right sort of light at the right time.

In this episode, he reveals the dangers of modern LED lighting, which often emits bright but unhealthy "junk light." Just as junk food wreaks havoc on our body, junk light disrupts our circadian rhythms, suppresses melatonin, and contributes to chronic diseases.

We cover:

💤 The Health Risks of LED Lighting: "junk light" disrupts circadian rhythms, suppresses melatonin, and contributes to chronic diseases

💡 Junk Light and Lumens - modern lighting regulations prioritise energy efficiency over human health

🕒 Circadian Clocks and Longevity: light is essential for disease prevention and healing

👓 Rise of Myopia in Children: indoor living and reduced exposure to natural light are fueling skyrocketing rates of myopia

🌈 Blue light blocking glasses - do you have the right sort?

🛠️ Practical Solutions for Healthier Lighting: simple changes you can make in your home and your life

Backed by decades of evidence, Dr Martin Moore-Ede shares the science behind why we must prioritise light in our health, and how to optimise our exposure for immediate benefits, and a longer, healthier life.

Find Dr Martin:

Mentioned in this episode:

Health and Light by John Ott

SORAA - light bulbs

The Body Electric by Robert Becker and Gary Seldon

Avoidance of sun exposure is a risk factor for all-cause mortality: results from the Melanoma in Southern Sweden cohort

Want to watch this on video? Subscribe on YouTube

Instagram @degreesofhealth

A randomized trial of pharmacological ascorbate, gemcitabine, and nab-paclitaxel for metastatic pancreatic cancer

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Dr Joseph Cullen, MD | Doubling Survival in Cancer Patients - The Science Behind IV Vitamin C

Wed, 01 Jan 2025 07:00:56 GMT

Here we're speaking with Dr. Joseph Cullen as he discusses his research on high dose intravenous (IV) vitamin C as a treatment for metastatic cancer. The aim in his lab is to show that adding high-dose, IV vitamin C, which is very inexpensive and very well tolerated, can improve treatment for these cancers that are among the deadliest. Joseph highlights the potential for it to transform not just patient outcomes but the entire conversation around alternative therapies. He shares candid insights from his lab’s work on glioblastoma, lung cancer, and pancreatic cancer, as well as ongoing studies into combining vitamin C with other treatments like immunotherapy and radiation.

We cover:

💡 What makes high-dose IV vitamin C a game - changer in cancer care

📈 Cancer progression and survival outcomes - his research that shows doubling progression-free survival

🔍 Mechanisms of action - pro-oxidant in cancer cells, antioxidant in healthy cells

👩‍⚕️ Challenges in acceptance - why some oncologists remain skeptical

🩺 Who benefits most - which cancers respond best, combining therapies, and where it doesn’t work

⚠️ Side effects and safety - what to watch for, including rare risks

The research shows significant promise, but challenges persist. Joseph opens up about the difficulties in securing funding for anything outside pharma-driven drugs and compounds, the skepticism from traditional oncology, and the need for more extensive clinical trials to validate findings. Despite these hurdles, his belief in the therapy’s potential remains steadfast - and his surprise at just how well it works, over and over again, keeps driving him forward.

Mentioned in this episode:

High-dose IV vitamin C plus chemotherapy doubles survival in advanced pancreatic cancer

What is metastatic pancreatic cancer?

Find Joseph:

joseph-cullen@uiowa.edu - Joseph kindly said that oncologists can reach out to him directly to enquire more and request the protocol for patients where appropriate

All Dr Cullen’s papers

Free Radical & Radiation Biology

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Instagram @degreesofhealth

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Professor Thomas Seyfried | Cancer as a Mitochondrial Metabolic Disease

Wed, 18 Dec 2024 00:00:56 GMT

Meet Professor Thomas Seyfried, the biologist leading a revolution in how we fight cancer and other chronic diseases with metabolic therapies. Author of the acclaimed book 'Cancer as a Metabolic Disease', Professor Seyfried talks through the evolutionary biology behind cancer and the scientific evidence that disproves the consensus theory on the origin of cancer. His focus on the need for mitochondrial health and metabolic therapies opens up the conversation for new avenues of treatment that are less toxic and, quite possibly, more effective.

We cover (+much more):

🥬 How cancer cells thrive on fermentation - and how this changes treatment approaches

📉 The future of cancer care - rethinking research, funding, and patient education

🥩 Ketogenic diets and cancer

💊 Glutamine inhibitors and parasite drugs - tools with potential in fighting metastatic cancer

⚠️ The cost of traditional care - understanding why metabolic therapies may work better than or in addition to SOC

🌍 Why mitochondrial health matters – for cancer, diabetes, Alzheimer’s, and more

Professor Seyfried is astounded by how many cancer patients start to use metabolic therapy only after they've exhausted all other options and they haven't worked. He believes the first thing you need to do is get your body into NK, whatever treatment you choose. For patients, researchers, and anyone interested in the future of cancer care, this episode presents the latest metabolic science and the latest framework for cancer prevention and treatment strategies.

You have to ask - are we literally tripping over the truth here?

Find Thomas:

Twitter

All of Professor Seyfried's published work

Book - Cancer as a Metabolic Disease

Mentioned:

Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells

Press-pulse: a novel therapeutic strategy for the metabolic management of cancer

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Instagram @degreesofhealth

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L.J. Amaral, MS, RD, CSO | The future of oncology isn’t just in the lab - it’s on your plate

Wed, 11 Dec 2024 00:00:04 GMT

LJ Amaral dives us deep into the world of metabolic therapies and the ketogenic diet as a potential treatment for cancer. LJ shares valuable insights into the promising intersection of diet and cancer care and her pioneering research in the field makes this a must-listen for anyone interested in personalised cancer treatments and improving quality of life through dietary changes.

We cover (but so much more too):

📖 The Warburg theory - understanding a cancer cells’ glucose dependence

🥑 Getting the fat equation right - omega-3s, whole fats, and tips for sticking to a high-fat diet. And why fat matters more than protein here...

🫒 Keto vs. Keto for cancer - dramatic tumour reductions and improved patient-reported outcomes in fatigue and cognition

💡 Future research - ketosis thresholds, 428 ongoing clinical trials, and personalised metabolic therapies

🩺 Patient-centered care in cancer treatment - respecting choices while providing evidence-backed support

🌟 BHB and inflammation - how ketones stabilise damaged cells and improve outcomes

LJ Amaral’s commitment to extending healthspan and improving quality of life shines through. Her belief in the importance of maintaining hope and collaboration between patients and clinicians is inspiring.

Find LJ:

Research Gate

Mentioned in this episode:

Keto Nutrition.org - also see our episode with Dom D’Agostino

Charlie Foundation

Keto Mojo by Miriam Kalamian

Tools of Titans by Tim Ferriss

Untethered Soul by Michael Singer

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Instagram @degreesofhealth

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Lauren Kennedy-West | From Schizophrenia to Symptom-Free - Metabolic Therapies for Mental Health

Wed, 04 Dec 2024 00:00:48 GMT

What if the way we think about mental health is due for a revolution? Maybe we don’t need to suffer and to 'try to' live well with the big challenges that mental illness can bring - maybe we can actually...live well.

In this deeply personal and groundbreaking conversation, Lauren Kennedy-West shares her experience of living with schizoaffective disorder - and historical diagnoses that included depression, bipolar disorder with psychotic features, and an eating disorder - to living symptom-free and off psychiatric medications. What she did? After years of psychotic episodes, anti-depressants, and anti-psychotics, Lauren made a decision not centred on treating the symptoms but on improving her underlying metabolic health. Lauren adopted a strict medical ketogenic diet and metabolic therapies that healed her brain and transformed her life.

What if we removed the dogma on how we currently understand mental health - for just a moment - and were to ask 'what if we are wrong?' - what might we be able to see? Heads you win big, tails you don’t lose much. And in Lauren's case, she won big

We hope this episode serves as a safe space to explore ideas that may challenge the status quo and offer immense hope for anyone thinking "there must be something more I can do". There is. Lauren's story provides powerful insights into what is possible when we address the root causes of mental illness, serving as a beacon of hope and inspiration as to what is possible for a better tomorrow.

Find Lauren:

Metabolic Therapies for Mental Disorder

Online peer support communities:

Schizophrenia Peer Support Community

Additional resource for Metabolic Therapies for Mental Health:

Metabolic Mind website

Metabolic Mind YouTube channel

Mentioned in this episode:

Gut and Psychology Syndrome by Natasha Campbell-McBride

Brain Energy by Chris Palmer

Chronometer App

Dr. Guido Frank

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Dr John Mulhall, MD | 70% of ED cases are vascular. Gents, here’s what that means for you

Wed, 27 Nov 2024 00:00:00 GMT

Dr. John Mulhall doesn't just treat erectile dysfunction (ED), he's also on a global mission to demystify its causes, highlight its complexities, and offer an alternative to how we currently think about sexual health.

This is for you if you’re wondering: what can I do today to ensure better sexual health tomorrow? Even if it's good today, don't you want to ensure it'll be good in your later years? And if it's not where you want it to be today, perhaps you've not spoken to anyone about it yet - you're not alone here. There are answers out there and support to be given. But you've got to ask for it.

We cover:

🏃 Exercise and erectile health - getting it up (your heart rate)

📈 Durability and frequency - it matters, but it should only matter to you

👨‍⚕️ Exogenous testosterone - risk of transference and its impact on fertility

💦 Premature ejaculation: lifelong vs. acquired - and what to do about each

💉 Navigating treatment options - pills, patches, and injectables and caution over the the ‘Wild West’ of supplements

💊 PDE5 inhibitors - how they work, their cardiovascular benefits, and their limitations

🧠 The psychology behind ED - how placebos enter in and integrating psychological and medical approaches for effective treatment

🔬 Emerging therapies - shockwave therapy, platelet-rich plasma, and penile botox injections - do they work?

His ultimate advice? Don’t wait to bring it up. Whether you’re a patient or a physician, empowering conversations can make all the difference.

Find John:

Twitter (@SaveYourSexLife)

Dr John's Book

Want to watch this on video? Subscribe on YouTube

Instagram @degreesofhealth

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Dr. Kate Balestrieri | Modern Intimacy and The Nuances of Sex: Trading Judgement for Curiosity

Wed, 20 Nov 2024 00:00:50 GMT

Just how judgey are we when it comes to sex? With ourselves, with our partners, with friends, when listening to others online... Be honest. What benefit does it serve? Or a better question to ask perhaps is what damage might it be doing?❗Whether you’re navigating your own relationship challenges or seeking deeper insights into your own sexual exploration, listen here to Dr Kate because it's a rich and honest conversation that might just reshape how you think about and experience intimacy, equality, and desire.

Dr. Kate, who has spent thousands of hours with individuals and couples in private practice, shares with us the complexities of sexual struggles that are often silenced. And what's most sad to Dr Kate is just how many people tolerate dissatisfaction in their relationships, and never experience the full potential of their intimate capacity.

We unpack a lot in this episode:

🤨 Can we trade out judgement for curiosity when it comes to ... well everything, but sex in particular?

🪝 Hook up culture - what happens when we only focus on individual rather than shared pleasure?

🖋️ Better sex education (not excl. anatomy + pleasure) and pleasure equity

👨 The challenges men face in being emotionally present balanced with still proving that they check all the boxes of 'what it means to be a man'

‍🍼 How intimacy evolves and changes (!) over time, the inequities of emotional labor and discrepancies in desire

Some tougher topics to face: --Why do happy people cheat? --How do trauma and dissociation impact intimacy? --What does it take to create the psychological and emotional space necessary for genuine connection?

Dr. Kate is relentlessly positive in her regard and nothing is off the table to explore. She shares actionable advice on how couples can work at building shared realities, breaking down barriers to arousal, and cultivating a sense of safety and play.

Mentioned in this episode:

She Comes First by Ian Kerner (see previous episode with Ian)

Come As You Are - Emily Nagoski

Kate Mann - Down Girl; Entitled

The Patriachs by Angela Saini

Everyday Sexism - Laura Bates

Yes, Mistress by Alicia Zadig

Find Kate:

ModernIntimacy.com

Podcast: Get Naked with Dr Kate

Book release Feb 2025 - What Happened To My Sex Life?

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Lily Nichols, RDN, CDE | The Fertility Factors: Blood Sugar, Protein, and Nutrient Density

Wed, 13 Nov 2024 00:00:53 GMT

This episode's information revealed just how much of our 'regulated' nutritional information is either completely outdated or incorrect. Here with Lily Nichols, a renowned dietitian and author who is not afraid to speak on the controversial dietary topics, we discuss where current nutritional guidelines on protein and micronutrients impact overall health and hold us back, particularly for those looking to optimise fertility and metabolic health.

Tune in to get the latest on:

🤰 Nutritional foundations for maternal and child health - pre-pregnancy, pre-natal, and post natal

🍩 Blood sugar regulation and nutrient-dense diets for prospective parents

ℹ️ The actually essential roles of non-essential amino acids

👶🏻 A protein-forward, nutrient dense intake for maternal health and fetal development

🌾 Supplementing vs real foods - the synergies

🧬 How nutrients (like choline, vitamin D, and B12) influence genetic expression from the womb onward

This conversation is a must for prospective parents, and anyone seeking to understand how optimal nutrition intersects with fertility, energy, and lifelong health.

Find Lily:

Website, Blog Posts and Books

Free 1st Book Chapter - Real Food for Pregnancy

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Dr Casey Peavler, MD | Cancer, Ketosis, and Control: Taking the Driver's Seat in Treatment

Wed, 06 Nov 2024 00:00:43 GMT

A powerhouse of knowledge, we're joined by Dr. Casey Peavler who invites us to address 3 impending needs: 1. for medicine to become less siloed 2. for doctors never to stop learning or being curious and 3. for patients to not lose their autonomy and agency in health treatments and decisions. Here, Ben and Dr Casey delve into the evolving understanding of cancer treatment, contrasting the traditional somatic mutation theory with the emerging metabolic theory of cancer. The conversation highlights the intricacies and nuances of new and promising routes to understand cancer and its treatment to remission. As with many of our conversations and guests, Casey emphasises the importance of patient agency and the need for informed decision-making in collaboration with healthcare providers.

We discuss:

🥼 Somatic vs. Metabolic Theories of Cancer - why our understanding of cancer needs to evolve and where they both have merit

🤏The Press Pulse Protocol - “starving” cancer cells while strengthening the body

🥥 Exogenous Ketones, Glucose, and Glutamine — Targeting cancer cells’ energy sources for effective treatment

🔅 Chronic low-level sun exposure for Vitamin D - crucial for both cancer prevention and treatment

💊 Dosing strategies - daily dosing of certain medications may be more effective than intermittent dosing for cancer treatment but context is key

🙋 The Power of Patient Agency — Moving from passive recipient to active participant in cancer care

Dr. Peavler urges patients to 'take the wheel' in their health journey. This conversation we hope will inspire you to explore all the avenues available to us when it comes to health, emphasising that you never lose the opportunity to be an agent within your own care - get information, learn, gather resources and identify what looks like a path to health for you. And we'd love to hear from you if you do.

Find Casey:

Integra Medicine

Mentioned in this episode:

Books by Dr Fung - The Cancer Code. The Obesity Code.

Study Douglas Wallace

Study Press-pulse: a novel therapeutic strategy for the metabolic management of cancer

Book Defeating Cancer!: The Biological Effect of Deuterium Depletion by Gabor Somlyai

Book The Plant Paradox by Stephen Gundry

Book Keto Fast by Joseph Mercola

Book - Cancer as a Metabolic Disease by Thomas Seyfried

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Instagram @degreesofhealth

Study Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes

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Dr Brendan Egan, PhD | Promise or Hype? Natural and Exogenous Ketosis for Performance & Recovery

Wed, 30 Oct 2024 00:00:39 GMT

More keto! We're interested in everything keto at the moment. The different ways to get into ketosis, how the body and brain respond to a ketogenic state, the complexities of exogenous ketones, and what possible benefits and drawbacks a state of ketosis has.

Dr. Brendan Egan this week helps us to dissect the current literature of ketones within the field of exercise performance and recovery, and offers a suggestion to look past ketones as a one-size-fits-all solution. Brendan also shares insight on the future of ketone research and the importance of focusing on foundational health practices.

We cover:

🥜 Natural ketosis - fasting and/or a ketogenic diet

🧪 Exogenous ketones explained: ketogenic precursors (MCTs), salts, esters, and dosage

🔬 The current data on ketosis and performance / recovery - the promising and the no-shows

😟 The potential value of ketosis when the body is really stressed

💪 Muscle protection - mitigating the effects of bed rest

💊 Placebo Power: Impacts performance and supplement perception.

If you're interested in using keto as a dietary intervention for exercise performance, recovery, or as a protective mechanism with reduced mobility or bed rest, have a listen. It certainly could be worthwhile seeing if shifting your body's fuel source helps you in your endeavour.

We'd love to hear from you - have you had any personal results that demonstrate anything similar to or contrary to the current literature?

Mentioned in this episode:

Study Ketone Bodies Attenuate Wasting in Models of Atrophy

Book Outlive by Peter Attia

Book Surely You’re Joking and What Do You Care What Other People Think? by Richard Feynman

Herology Women's Supplements

Find Brendan:

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Ian Kerner, PhD | Let’s Talk About Sex (Seriously, It’s Important)

Tue, 22 Oct 2024 23:00:52 GMT

Why are we scheduling dentist appointments but not sex? How do we tackle desire discrepancies—when one of us is in the mood while the other is wondering what’s on Netflix? And why is "performance anxiety" such a thing?!

Ready to dive into the nitty-gritty of what really makes relationships tick? We sit down with Ian Kerner - he’s got the answers to all those questions you probably didn’t ask at your last dinner party. From how common it is for couples to be inches apart physically but miles apart emotionally, to the very real consequences of deprioritising sexual attraction, this conversation is a masterclass in sex and intimacy.

We go into:

📢 Why sexual compatibility should be a top priority in relationships

🪜 Bridging the gap in desire differences

⏰ Performance anxiety and the male obsession with "lasting longer"

👑 The clitoris as queen: closing the orgasm gap

📅 Scheduling sex: Unsexy or genius?

👴👵 Keeping the flame alive in long-term relationships

We see all of you out there experiencing this and not asking the questions. So we did it for you. You're welcome! Watch, listen, take note, maybe even try a new approach. Whether you're in a relationship, looking for one, or just curious, this conversation might start you thinking that there's another way to think about sex for your relationship health - and it could just be better than what you've got now...

And let us know - what do you think? What other questions do you have? "Is it normal that...?" Has it helped? Are there more obstacles?

Find Ian:

Mentioned in this episode:

She Comes First by Ian Kerner

So Tell Me About the Last Time You Had Sex by Ian Kerner

The Erotic Mind by Jack Morin

Study - More Than Just Sex: Affection Mediates the Association Between Sexual Activity and Well-Being

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Dr Dom D'Agostino | Augmenting Cancer Outcomes: Ketogenic Diets, Caloric Restriction & Hyperbaric Oxygen Therapy

Tue, 15 Oct 2024 23:00:18 GMT

This podcast episode features an in-depth conversation on metabolic therapies and their potential in cancer treatment, particularly focused on glioblastoma and other glycolytic cancers. Our guest, Dr Dom D'Agostino, a researcher and professor with a diverse background in neuroscience, molecular pharmacology, nutrition and physiology, has a particular interest in metabolic therapies. Dr Dom shares how manipulating the body’s metabolism through the glucose ketone index (GKI), therapeutic ketogenic diets, and redox therapies can improve cancer outcomes by reducing tumour growth and enhancing standard treatments like chemotherapy and radiation. We also explore the synergies of non-toxic therapies such as hyperbaric oxygen, metformin, and IV vitamin C, and how these could potentially reduce the side effects and overall outcomes of cancer treatment.

We cover:

🩺 Standard cancer care with and without metabolic interventions

💊 Managing seizures with ketogenic therapies - a superior alternative to anti-seizure drugs

🍽 The power of fasting and the importance of protein intake in chemotherapy and cancer augmentation

🔥 Why certain cancers are more susceptible to metabolic-based therapies

🔬 How overall mitochondrial health dictates cancer cell transformation

Dom also touches on the fundamental relationship between liver health and cancer growth and metabolic strategies to prevent cancer. If you're interested in the intersection of nutrition and cancer or wondering how far we are from keto becoming part of standard care, this is a must-listen episode.

Find Dom:

Metabolic Health Summit YouTube

Metabolic Health Summit

Mentioned in this episode:

Cancer cases attributable to potentially modifiable risk factors

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

Ketones inhibit mitochondrial production of reactive oxygen species

The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival

Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer

Metabolic management of glioblastoma ...with a restricted ketogenic diet

Clinical trials in progress

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James O'Hara, NP | Hair Loss, Hormones and Health Optimisation

Tue, 08 Oct 2024 23:00:44 GMT

Are you struggling with hair loss and not sure where to start? Or perhaps you have a hormone profile back that you want to work to improve? Whether you’re dealing with hair loss, want to optimise your hormonal profile towards a specific goal, or just want to feel at your best, this episode is packed with a science-backed medical perspective to provide you with the information to make decisions that support your journey to better health.

James O'Hara, a nurse practitioner with a keen specialisation in preventative medicine, explores the science behind hair loss, hormonal balance, and how lifestyle choices impact these areas, and our overall well-being. If you’re seeking practical solutions for improving both your vitality and appearance, this episode is for you.

Key Discussion Points:

🔍 Root causes of hair loss – from iron deficiency to hormonal imbalances in men and women

⚖️ Balancing hormones and hair loss treatments – exploring total testosterone, DHT, dutasteride and finasteride

📚 Stacking for regrowth – combining lifestyle changes with other interventions e.g. microneedling, nutrient optimisation, red light

🥗 Diet and testosterone – how fat, carbs, and supplements can influence hormone levels

🔄 Testosterone Replacement Therapy (TRT) – who might benefit, and the risks involved

🧠 Cognitive Performance – Enhancing brain function with caffeine, Modafinil, and other low-risk tools

James emphasises the importance of a holistic approach, reminding us that no single treatment fits all. It’s about personalisation according to the individual, stacking therapies, managing lifestyle, and optimising nutrition for desired health outcome and long term well-being.

Find James:

Gillet Health Podcast

Study - Acute administration of roflumilast enhances sensory gating in healthy young humans

Mentioned in this episode:

Study - Acute administration of roflumilast enhances immediate recall of verbal word memory in healthy young adults

Study - Acute treatment with the PDE4 inhibitor roflumilast improves verbal word memory in healthy old individuals

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Use of medium chain triglyceride (MCT) oil in subjects with Alzheimer's disease

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Mary Newport, M.D. Part 2 | Brain Fuel: How Coconut Oil and MCTs Can Transform the Alzheimer's Brain

Wed, 02 Oct 2024 06:40:34 GMT

PART 2! If you or someone you love is affected by Alzheimers, this is for you. If you believe you’re at risk genetically or you want to prevent your own cognitive decline, this is also for you. If you’re curious about the role of ketones and the ketogenic diet in brain health, this is absolutely for you.

Find Mary Newport:

Website and Books

Mentioned in this episode:

Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease

Dr Stephen Cunane. Can Ketones Help Rescue Brain Fuel Supply in Later Life?

Low-fat versus ketogenic diet in Parkinson's disease:

Study due 2025: Refueling the post COVID-19 brain: potential role of ketogenic medium chain triglyceride supplementation: an hypothesis

A short history of saturated fat: the making and unmaking of a scientific consensus

Lauric acid promotes neuronal maturation mediated by astrocytes in primary cortical cultures

Metabolical by Robert Lustig

Cancer as a Metabolic Disease by Thomas Seyfried

Ravenous by Sam Apple

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Mary Newport, M.D. Part 1 | Brain Fuel: How Coconut Oil and MCTs Can Transform the Alzheimer's Brain

Wed, 02 Oct 2024 06:39:35 GMT

PART 1! If you or someone you love is affected by Alzheimers, this is for you. If you believe you’re at risk genetically or you want to prevent your own cognitive decline, this is also for you. If you’re curious about the role of ketones and the ketogenic diet in brain health, this is absolutely for you.

Dr. Mary Newport, neonatologist, author and certified Ketogenic Nutrition Specialist, shares her personal story of using a ketogenic diet to support her late husband, Steve, in his battle against early-onset Alzheimer’s. She explains the science behind ketones and how they serve as an alternative fuel for the brain. This episode doesn’t only offer insight into how ketones can improve cognitive function, mood, and overall quality of life, it also provides a very valid explanation for how they can be used to improve already existing cognitive decline.

We cover (but so much more too):

🧠 The brain-energy gap – how ketones bridge the gap

🥥 MCT oil and coconut oil – their structures and unique role in producing ketones

🍼 The connection between MCTs in breast milk and infant brain development

🔥 Ketones: anti-inflammatory, appetite-suppressing, and brain-protective properties

🩺 Can ketones prevent Alzheimer’s in high-risk individuals?

🔬 Research on ketone esters and future treatments for cognitive decline

Dr. Newport also touches on the need for more research into the use of ketones for Alzheimer's, the impact on inflammation and cerebral blood flow, and the challenges to traditional low-fat dietary guidelines. She emphasises the potential of ketogenic diets to improve brain health both in slowing the development of Alzheimer's and as a preventative measure, and discusses her upcoming book on dietary guidelines and brain ageing.

Find Mary:

Website and Books

Mentioned in this episode:

Reference list on Mary Newport's website

Full reference list can be found in Part 2

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William B. Irvine | Your Guide To The Good Life - from a 21st Century Stoic

Tue, 24 Sep 2024 23:00:55 GMT

If you feel like life is slipping by and you're unsure how to live with purpose or intention, this episode is for you. William B. Irvine - author, philosopher, teacher and practicing Stoic - shares profound insights on how Stoicism offers a coherent framework for living a fulfilled life. Bill encourages us to embrace discomfort, fail forward, and live authentically—not for social approval but for personal fulfilment. Whether you're new to Stoicism or a seasoned practitioner, this conversation offers actionable insights to help you master the art of living well.

🧠 The psychology of Stoicism: controlling negative emotions, not avoiding all feelings

⚖️ Hedonic treadmill: why chasing happiness may not lead where you think or want

🎯 Living by your values: how Stoicism and Zen Buddhism align in focusing on what truly matters

🌀 Negative visualisation: a Stoic practice for cultivating gratitude and perspective

🔄 Reframing challenges: using a positive mindset to turn obstacles into opportunities

Listen in here if you are interested in carefully rethinking the assumptions of everyday life and how they affect all realms of your health.

Find Bill:

Mentioned in this episode:

Book - A Guide to the Good Life: The Ancient Art of Stoic Joy by William B. Irvine

Book - On Desire by William B. Irvine

Book - The Stoic Challenge: A Philosopher's Guide to Becoming Tougher, Calmer, and More Resilient by William B. Irvine

Book - Walden by Henry David Thoreau

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*Study - Interconnected Dynamics of Sleep Duration, Social Media Engagement, and Neural Reward Responses in Adolescents

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Dr Mitesh Patel | YOUR MIND MATTERS - Tele-Therapy, Tech, and Transformation in Mental Health

Tue, 17 Sep 2024 23:00:31 GMT

Mental health - we all have it. Yep, even you.

We are all getting so good at looking after the various aspects of our physical health - nutrition, types of exercise, light exposure, cold baths - whatever your bag is, we're here for it. And many are catching on that the same approach can be used to look at aspects of our mental health. There are things we know make us feel great and then things we do that make us feel... well, not so great. We're human and we have and will continue to get that balance wrong a lot. But we believe part of getting it wrong a little less is being aware of what those things are. Enter the world of therapy that can help us with this process of discovery, identification and support in understanding our rationale behind behaviours that no longer serve us present day and illuminating a world in which we might be able to make differences choices.

Here, we're speaking with Dr. Mitesh Patel discussing mental health and psychiatry. Mitesh talks about the pyramid of sound foundational principles - what we can do to foster sound mental health - and offers a unique perspective of what this field of work is highlighting at the moment. We cover:

💭 Mistruths around what it means to mentally well

💛 Emotional language mapping for young children in schools

🚫 Social media diets

🥽 The future of psychiatry - in-person, telehealth therapy, VR therapy

🛠️ Psychedelics for positive change - micro dosing, assisted therapies, guided trips

Find Mitesh:

Mentioned in this episode:

Film - Her

Film - Ready Player 1

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Professor Glen Jeffery | Red Light Revolution: Charge Your Cells, Reduce Ageing & Decrease Inflammation

Tue, 10 Sep 2024 23:01:51 GMT

If you use a red or near-infra red light and you don’t really know why or what wave length you’re working with - this is for you. If you don’t even know why you would use a red light or want/need exposure to it, this is also for you.

Glen Jeffery Professor of Neuroscience at UCL, explains the profound impact of light on our cellular health, particularly through the lens of mitochondria—the energy powerhouses of our cells. He explains how different wavelengths, especially red and near-infrared light, can recharge these cellular batteries, improving metabolism and reducing the effects of aging and inflammation.

💡Relationship between light and high energy demanding systems of the human body

🔋Mitochondria as a light-sensitive battery

🚨Red light penetration just how far does it go through the body?

🏥Application outside the lab - could changing the light bulbs in hospital reduce bed occupancy?

❤️‍🩹Wound healing with red light

〰️Red light vs near infra red light - it’s all about the wave lengths.

Glen - “I’ve told everyone in the lab we’ve got to stop doing science and we need to start talking” - people need this information.

Where to find Glen:

UCL Website

Mentioned in this episode:

Study - Light stimulation of mitochondria reduces blood glucose levels

Study - NASA Research Illuminates Medical Uses of Light

Book - Power Sex and Suicide by Nick Lane

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Dr Karen Doll | Self-Awareness to Self-Discovery: Psychological Fitness and Effective Change

Wed, 04 Sep 2024 07:46:01 GMT

We all have that tendency to go against our own better judgement when it comes to making decisions for our health - but why do we do it when we know there’s a better option there for us? The frustration it incurs! Not to mention the time wasted… and the guilt. It most certainly isn’t a lack of information available on how to be happy and healthy - that’s abundant. So, why is it that we often don’t actually do the things we know we should?

We ask this and more with psychologist and coach, Dr Karen Doll. Karen practices what she preaches in supporting high performers with tools for psychological fitness. She asks the million dollar question - is it possible to be challenged, strive, achieve and grow without unnecessary anxiety and distress? Karen believes it absolutely is. The key? We have to be intentional about it.

We dive into:

⚖️ Sweet spot of energy and vitality without unnecessary anxiety and distress

💗 You’re never the only one struggling

🌎 “Not Enough” - a universal of human experience

🎯Why we self-sabotage and challenging core beliefs

💼📊Comparison, workaholism and successism - external to internal acceptance

📱Smart phones for psychological fitness - generative or destructive?

A big thought point for us was the following question and we’d love for you to explore it too and see how it applies in your own life. If we don’t know ourselves or what we want to be different, how will we even start the process of change?

Find Karen:

Harvard University Flourishing at Work Network

Mentioned:

Book - Building Psychological Fitness by Karen Doll

Book - The Anxious Generation by Jonathan Haidt

Roulette - Addiction by Design by Natasha Dow Schull

Book The Good Life by Robert Waldinger

Book Fallen Leaves by Will Durant

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Ice Bath and Cancer Science

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Dr Thomas Seager, PhD | The Metabolic Theory of Cancer: Mitochondrial Defects, Cold Water and Ketosis

Wed, 28 Aug 2024 04:00:39 GMT

Thomas Seager joins us again for a conversation challenging the conventional understanding of cancer. Thomas argues that the war on cancer, launched over 50 years ago, has failed to make significant strides in combatting the disease due to a fundamental misunderstanding of its origins.

With scientific clarity, Dr. Seager explains:

🔬the theory of cancer as a metabolic disease, beginning with defects in mitochondrial DNA, rather than the previously believed nuclear DNA

🍯 how glucose metabolism plays a crucial role in cancer growth

💧 ketosis and cold exposure therapies in inhibiting tumour growth

🏆 inspiring case studies using cold water to combat cancer (see episode with Dean Hall)

⚠️ the limitations of traditional cancer treatments (chemotherapy and radiation) and the need for more research and openness towards alternative and/or adjunct therapies focused on metabolic health, mitochondrial function, and lifestyle choices.

If you know of someone with cancer at the moment, share this with them. Or better yet, read the papers and books mentioned below and entertain the possibility that there may be additional things you can do to revolutionise their cancer care and improve the prognosis for a loved one. Surely that's worth a read.

Find Thomas:

Substack

Twitter & Instagram: @seagertp

Mentioned in this episode:

Book: Uncommon Cold by Thomas Seager

Study - Cancer as a metabolic disease: implications for novel therapeutics

Study - Can the Mitochondrial Metabolic Theory Explain Better the Origin and Management of Cancer than Can the Somatic Mutation Theory?

Book - Cancer As A Metabolic Disease by Thomas Seyfried

Study - Brown-fat-mediated tumour suppression by cold-altered global metabolism

DNA repair and anti-cancer mechanisms in the longest-living mammal: the bowhead whale

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Professor of Behavioural Psychology John Parkinson | "When do we stop and think, I can change this"?

Wed, 21 Aug 2024 04:00:05 GMT

We can all talk a good game - but how often do we actually deliver on the goods? If we know what we need to do to feel good, to attain and maintain good health, and achieve our goals and desires - why is that we find ourselves not doing the things?! Professor John Parkinson and Ben dive head first into the theories of behavioural psychology behind these patterns in us - where they come from, why they develop and what we can do to change them.

Here we cover:

🎯 The Intention-Action Gap

💡 The need for specificity in setting and achieving goals

🧠 Optimists and pessimists - do you believe you can or you can’t?

🏆 Fear of failing - we all know it, so what do we do with it?

🎲 Gamifying life - “how would you live differently if you viewed life as a game?”

👫 Gender differences in achievement, and optimism.

💪 Self-determination theory and 3 core motivating categories

Listen in to John and Ben's open discussion on how to stack the deck in your favour through understanding what is driving our behaviour, self-awareness and optimising your environment for goal achievement.

Find John:

Psychology Students’ Marathon Achievements

Public Health Wales - Behavioural Science Unit Website

Wales Centre for Behavioural Change blog

Mentioned in this episode:

Book - Super Better by Jane McGonigal

Study - Motivation and Behaviour Change in Parkrun Participants

Book - Thinking Fast and Slow by Daniel Kahneman

Book - Determined: Life Without Free Will by Robert Sapolsky

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Dr James Kinross | A Microbiome Masterclass: The Dark Matter Within Us

Wed, 14 Aug 2024 05:00:11 GMT

Dr. James Kinross, a leading consultant surgeon and lecturer at Imperial College London, isn’t just at the forefront of gut microbiome research—he’s also written the book on it. Dark Matter delves into the vital role micro-organisms play in our bodies and the profound impact their balance (or imbalance) has on our health. Dr. Kinross’ research explores how the gut microbiome seemingly influences everything about how we interact with our environment and the impact it has on our health and our life as we age.

Here, we discuss:

👤 The symbiotic relationship between humans and their microbiome

🚨 Bowel cancer: Why 95% of cases Dr Kinross operates on are preventable

💊 The global misuse of antibiotics and its consequences

💩 Fecal microbiome transplants—yes, it’s a thing!

🧠 The crucial link between gut health and mental health

🔬 The challenges of modern medicine working in silos

📊 The future of microbiome science as a tool for population health

Dr. Kinross is shaping our understanding of the hidden world within us, and this conversation might just change the way you think about looking after it.

Find James

Book - Dark Matter

Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients

Mentioned in this episode:

Sweaty T-Shirt Experiment

Are single odorous components of a predator sufficient to elicit defensive behaviors in prey species?

The Human Gut Microbiome as a Potential Factor in Autism Spectrum Disorder

The Age of Surveillance Capitalism - Shoshana Zuboff

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Kristi Storoschuk, PhD(c) | A Metabolic Love Story: High-Intensity Exercise and Your Mitochondria

Wed, 07 Aug 2024 05:00:34 GMT

Kristi Storoschuk couldn't sit back on her laurels and only write about science, she followed her academic curiosity into conducting the research herself, to deepen all of our understanding of metabolic health, healthy ageing and prevention of chronic disease. Kristi is active in developing a career around science communication and truly believes understanding why we make a lifestyle change dictates how well it we stick with it.

Kristi is making a real difference in the health industry, and we're grateful she took the time to tell us how. Here, we cover:

🙂 How we can improve our metabolic health with high intensity exercise (and why we should care about it)

📈 Where is what you're doing going? - the trajectory of your health activities

👟The many ways to achieve a health outcome - one size might not fit all here!

💪 Muscle mass vs muscle quality - yep, there's a difference

🏃Carbohydrate feeding vs fasted exercise

😮‍💨 VO2 max, mitochondrial content and metabolic health

Kristi practices what she preaches and loves a challenge - we're talking triathlons on a whim, self-scripted high intensity workouts, EMOMs - just take a look at her instagram for inspiration and to try one out for yourself.

Find Kristi:

Mentioned in this episode:

Right Thing Right Now - Ryan Holiday

Jordan Jonas on Lex Friedman Podcast

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Dr Felice Gersh, MD | The No.1 Cause of Female Infertility... and What You Can Do About It

Wed, 31 Jul 2024 05:00:38 GMT

Here, with globally recognised women’s health expert Dr Felice Gersh, we talk about PCOS. Polycystic Ovary Syndrome is on the rise with 1 in 10 women currently suffering with or managing the condition - sadly, most are the former. The imbalance affects the entire metabolic system and leads to inflammation, fatigue, and perhaps most prevalent in the reproductive era, fertility issues - it is the number one cause of female infertility. Quite right that this requires plenty of attention then.

Dr Felice Gersh explains where we may be exacerbating the problem (birth control pills), but also where there is scope to reduce PCOS symptoms (shifts in lifestyle) that serve to address the underlying cause of the condition.

We go into:

🤰PCOS - what it is, why it’s on the rise, and the knock on inflammatory health and fertility implications

🧠Endotoxins, inflammation in the body and the brain

🍓Fertility as a sign of health

💊The birth control pill - why to exercise caution using BC for acne and facial hair

♀️The use of GLP1, Metformin, Bioidentical Hormones and Lifestyle Medicine for improvement in PCOS and overall health.

If you are looking to find out more about PCOS and how to manage it, Dr Felice makes the science of what us happening in the body very accessible, and also provides expert advice on what to do that proactively aids its management.

For much more on PCOS and women’s health, find Felice at the links below:

PCOS SOS: A Gynecologist's Lifeline To Naturally Restore Your Rhythms, Hormones, and Happiness

Link Tree

IMGI

Google Scholar - all published articles

Books: Menopause: 50 Things You Need to Know

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Dr Lauren Burns, PhD OAM OLY | An Olympic Mindset Masterclass

Wed, 24 Jul 2024 05:00:42 GMT

The opportunity to sit down with an Olympic gold medallist is a rare one - but an even rarer opportunity is to speak with an Olympic athlete-naturopath-nutritionist-performance coach-author-keynote speaker in one. Don't believe us? Introducing Dr Lauren Burns, PhD OAM OLY. Lauren has a unique perspective of how we can each tap into our inner resources to bring about desired outcomes in our lives and has developed her career to foster that in others through her coaching, speaking and books.

Here, Ben and Lauren discuss:

⭕ The Circle of Lifestyle - Lauren's holistic method to elevate individual potential

🔄 Supportive networks and feedback loops in and out of high-performance sports

⌛ 20-Year Plans and Seasonal Plans - where people struggle most with goal-setting

🤝 Stress resilience in relationships - the benefits of quality alliances

🧍 Personalised medicine and tailored health practices

💭 Reframing negative self-talk

If you don't get the opportunity to watch the whole thing - we invite you to think about this question from Lauren: When you get to the end of your life, what do you want to look back and have done? Life is too long not to.

Find Lauren:

-Supportive interpersonal relationships: a key component to high-performance sport

Lauren’s Books: Fighting Spirit (autobiography) & Food from a Loving Home (cookbook)

Mentioned in this episode:

Lending a Hand: Social Regulation of the Neural Response to Threat

-Lifestyles and mindsets of Olympic, Paralympic and world champions: is an integrated approach the key to elite performance?

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Study - Effect of early and late light exposure on the inherited retinal degeneration in rats

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Professor Russell Foster | "The quality of your life is downstream of your circadian biology"

Wed, 17 Jul 2024 05:00:56 GMT

Russell Foster is a Professor of Circadian Neuroscience and the Head of Department of Ophthalmology at the University of Oxford. Russell has received globally renowned prizes, medals and awards for his discovery of non-rod, non-cone ocular photoreceptors - which he explains in this episode is revelatory in our understanding and application of circadian biology.

Here, we learn:

😴 Disrupted sleep-wake cycles and associated health issues

⏰ Sleep individuality - aligning sleep-wake patterns with your biology

🔵 Blue light blockers may not be as effective as previously thought

💤 Melatonin as a mild modulator of sleep and not a sleep hormone

👫 Gender differences in the circadian system - and the future of this research

💡 Potential of light therapy to optimise sleep and treating sleep-related disorders

Find Russell:

Book - Life Time

Research papers

Mentioned in this podcast:

Lux Measurement Apps - search on App Store

Study - Sex Differences in Behavior and Learning Abilities in Adult Rats

Study - Efficacy of cognitive behavioural therapy for sleep improvement in patients with persistent delusions and hallucinations

Study - Shift Work Disorder Among Oil Rig Workers in the North Sea

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Dr Gabrielle Fundaro, PhD | Body Image Disturbance - Self-Worth, Self-Trust and Freedom with Food

Wed, 10 Jul 2024 07:25:19 GMT

Dr Gabrielle Fundaro, PhD, is educated in several areas of academia including human physiology in exercise and sport, skeletal muscle and hyper trophy, microbiome and metabolism, and gut health. More recently, Gabrielle has aggregated this knowledge and turned her focus to dismantling diet culture and weight stigma through nutritional coaching. Gabrielle supports her clients to build confidence outside of our external physique and synergise self-awareness with nutritional knowledge - all with great compassion having had her own years with body image disturbance and a misplaced definition of 'healthy'.

This episode covers:

•Unlearning the diet narrative, weight stigma and ‘smallness=healthier’ in the female physique

•Body image disturbance and disordered eating masquerading as ‘health’

•Self-worth, self-trust and freedom with food

•Hunger training and habituation - are we eating for satiety and satisfaction, or something else?

•Interoceptive sensitivity and awareness - learning to trust internal cues again with RPE eating cycles

This episode is for you if you have ever felt like:

you have a very considered, careful, analytical, fearful, strict or restrictive relationship with food and or your body

your self-worth is based on your weight or physique

Having spent some time with Gabrielle, I wish I had met her when I had needed guidance with body image disturbance and disordered eating. I believed I was stuck in that loop for all eternity but thoughts equally tormented me that if I didn't change something, I'd live only a half life. The journey was lonely, uncertain and very bumpy. Now, I have so much freedom and confidence in what I can achieve with my body when I take care of it properly, but I wish I'd had someone like Gabrielle around offering a safe, personal and considered space to support the process. If you find yourself reading this thinking - it will never change, I'm stuck like this, or even maybe you see a way out but don't know if you really want to change it because you're scared of possible weight gain and food freedom (we see you), please get in touch with Gabrielle - it could just be the best health decision you ever make.

Find Gabrielle:

Link Tree

New Podcast - Salto De Fe. Leap of Faith.

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Dr Luana Colloca, MD, PhD, MS | Life: One Big Placebo Effect?

Wed, 03 Jul 2024 05:00:16 GMT

Dr. Luana Colloca disseminates the value, practical and ethical use of placebos. How powerful are they and how much influence do they hold in our lives? Luana holds an MD, a masters degree in Bioethics and a PhD in Neuroscience. From her contribution and research, she has developed an international reputation as a leading scientist on the neurobiological mechanisms of placebo and nocebo effects. In this conversation, we found ourselves asking more than ever, is life just one big placebo effect?

In this episode, we cover:

🤕Placebos and pain - managing symptoms we don’t understand yet

🧠Placebos and neuroplasticity - when things change in our brain, they change how we see the world

🍹Positive and negative environmental cues, context and individual variability. Why do we still feel tipsy drinking non-alcoholic drinks?

💭Thoughts as placebos - "I can do this", "I’ve got this" - just how much of our reality starts in the mind?

👥Mass-psychogenic phenomenons - nocebo effects at the population level

⚖️The ethics of placebos - to use or not to use

Find Luana:

Oxford University Press Book - open access. Also here.

Website - Placebo Beyond Opinions Centre

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Dr Anna Schaffner, PhD | Burnout Coach on Conquering Overwhelm, Beating Burnout and Rediscovering Your Purpose

Wed, 26 Jun 2024 05:00:48 GMT

Anna Schaffner, PhD, is a former academic who, after suffering the impact of burnout herself, turned her experience into a much-needed support for others to overcome burnout and reclaim a sense of balance in their work and life.

This episode is for you if:

•you think you’re burnt out - it will help you identify it and offer ways to support you shift out of it

•you’re an employer looking to improve internal programmes and processes to avoid burnout in your work force

We cover:

❤️‍🔥The ‘passion piece’ in work - inspiring or misleading?

😪The signs and symptoms - what causes burnout? Expectation vs reality, toxic work environments, resources and appreciation

❌Saying no. Perpetual people pleasing, perfectionism and negative inner critics

⏰The 80/20 principle and bucketing your areas of control

🎭The joy of hobbies, pleasure and play in making you more successful

Find Anna:

Free download - Overcome Burnout and Overwhelm: 7 Steps Towards Thriving

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How High Fives are Proven to Improve Culture and Performance

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Dr Michael Platt, PhD | Secrets of the Social Brain - Decision Making, Reciprocity and Bias

Wed, 19 Jun 2024 05:00:22 GMT

Dr Michael Platt is known for asking some of the most challenging questions in 21st century neuroscience—and conceiving innovative ways to find the answers. His principal questions focus on the biological mechanisms that underlie decision-making in social environments - why do we make the decisions we do and how conscious of these processes are we? This episode covers:

📉The value of reciprocity and the neuro-economics of decision making

🥀Waning social connection and species decline - are we in an age of despair?

🌎How unconscious and implicit bias works - diversity as a route to equity

🐒How monkeys predicted the US poll outcome

🤝Synchrony, shared mindset, and physiological alignment in group decision-making and cooperation

Find Michael:

Platt Labs Website

Book - The Leader’s Brain

Mentioned in this episode:

-Chimp Empire documentary

Risk factors for faster aging in the brain revealed in new study

Influence - Robert Cialdini

Early predictors of successful military careers among West Point cadets

The Psychology of Human Misjudgement - Charlie Munger (Farnham Street write up)

Thinking Fast and Slow - Daniel Kahneman

Human fertility is declining steeply and might presage our species' collapse

The Children of Men - Film, P.D. James

Countdown - Shanna Swan + Stacey Colino

Klara and the Sun - Kazuo Ishiguro

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Dr Wendy Suzuki | Upgrade Your Brain, Enhance Your Memory and Indulge in Neurochemical Bubble Baths

Wed, 12 Jun 2024 05:00:40 GMT

Dr Wendy Suzuki is a Professor of Neural Science and Psychology in the Center for Neural Science at New York University. Here, we cover how to get a big, fat, fluffy hippocampus (nb: you want one!) and bubble baths for your brain. No hidden agendas - it sounds as fun as it is, and it's just as good for you. Dr. Wendy Suzuki oozes energy and enthusiasm, guiding us how to embrace the potential of our brains throughout our lives.

We explore:

🏃 3 key effects on our brains when we exercise (+the short and long term benefits, BDNF and intentional exercise)

🍯 4 things that make new memories stick

🧘 the power of mindset and meditation on brain health

👫 the role of social connection for learning in cognitive function - and what Wendy is excited to see unfold in this area

🦸 anxiety as our superpower

🤩 Wendy's method to learning new things. Spoiler: it involves a lot of fun

Find Dr Wendy:

An Exercise-Meditation Smackdown

Masterclass: ‘Brain Health’ - releasing June 13th 2024

Books - US ‘Good Anxiety’. UK ‘Anxiety is your superpower’. Healthy Brain, Happy Life.

Mentioned:

Mind-set matters: exercise and the placebo effect

Buddha's Brain: Neuroplasticity and Meditation

Daniel Brevick - Opera singer

Elizabeth Strout - Author

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Dr Tommy Wood | Tools for Better Brain Fitness At Any Age

Wed, 05 Jun 2024 05:00:15 GMT

We all carry misconceptions about brain development, learning and adaptation - the fact that it can't change is the biggest of them all. Enter neuroplasticity and Dr Tommy Wood - a walking google scholar whose message is simple - we can change how our brain is ageing at any time.

This discussion on cognitive function explores:

-the significance of physical movement and mental stimulation

-the impact of retirement on age-related cognitive decline

-the role of arousal, sleep, and environmental factors (what F1 drivers do to get their brain in gear)

-the influence of beliefs, skills, APOE4 gene, supplements, and resistance training

Find Dr Tommy:

-Working Conditions and Early Retirement: A Prospective Study of Retirement Behavior

Podcast

Substack

Studies/Books mentioned in this podcast:

-Sensitive Periods for Visual Calibration of the Auditory Space Map in the Barn Owl Optic Tectum

-Demand Coupling Drives Neurodegeneration: A Model of Age-Related Cognitive Decline and Dementia

-Stress and multitasking in everyday college life: An empirical study of online activity

-Brain HQ

-The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER): study design and progress

Lisa Mosconi - The Menopause Brain + The XX Brain (Empowering Women to Prevent Dementia)

The Yerkes Dodson Law

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Dr Julie Radlauer-Doerfler | The Power of Courage for Connection

Wed, 29 May 2024 05:00:59 GMT

Most of us think social connection is a squishy topic—subjective and hard to define. And while there's much truth to this, there is no doubting the profound scientific data highlighting just how critical social connection is for all aspects of our health. It’s in our bones. We are wired to connect.

Here with Dr Julie Radlauer, we discuss the social influences of mental health - namely Social Connection • Social Support • Social Capital • Social Media • Social Justice. Knowing these social influences isn't hard, but navigating and implementing them isn't always easy, and so Julie provides us science-based insights and actionable steps to help us support ourselves and others. If you struggle to ask for help, give help, find support, or connect with others during difficult times, listen to Julie. Her warmth and experience offer universal comfort and practical guidance.

Dr Julie is a leading expert in the social influences of mental health and uses her experience to create impact within communities, systems, organisations, and individuals. As a doctor of public health and a licensed mental health counsellor, Julie’s work aims to answer why so many people struggling don’t access services and more importantly, how these people want to have their health needs met.

Find Julie:

Julie's Book - Connect: 100 Ways to Create Happiness in Your Life

TED talk

Mentioned in this podcast:

Adam Grant - Give and Take

Lean on me - Bill Withers

You’re Invited - Jon Levy

Caste: The Origins of our Discontents - Isabel Wilkerson

Believe in People - Charles Koch

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Dr Stephen Seiler, PhD | 80/20 Endurance Training: Go Slow, Get Fast

Wed, 22 May 2024 14:07:07 GMT

“The goal is not to destroy yourself”. Through his career with high level athletes and his research publications related to endurance training and intensity distribution, Dr Stephen Seiler, PhD, realised the damage in the ‘no pain no gain’ narrative. Here, we explore why the most effective training regimens emphasise sustainability over intensity and why rest days and consistent "Green Zone" activities are the backbone of superior athletic performance.

Stephen breaks down his polarised training model and shares insights on the 80/20 principle in application to your weekly/monthly schedule of training, and how reducing training complexity can lead to better results and a more enjoyable process. If you are:

-training for an event/marathon/triathlon

-looking to understand if VO2 max is the right metric for you to measure

-want to understand how elite athletes optimise their workouts

...this episode offers valuable strategies to enhance your endurance efficiency with less injury.

Dr Stephen Seiler, PhD, is an exercising physiologist who teaches, researches and leads on the topic of physiology and training adaptations, particularly in regards to endurance training. While anchored in an academic environment, Dr. Seiler has also served as research consultant and scientific advisor for a research foundation, sports teams, a regional hospital, and the Norwegian Olympic Federation, as well as founding the Elite Sport Performance Special Interest Group in 2014 at the European College of Sport Science.

Find Stephen Seiler:

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Dr Prerna Varma, Phd | Insomnia and Circadian Rhythm Disruption

Tue, 21 May 2024 18:17:22 GMT

This episode explores the 3-P model of insomnia (Predisposition, Precipitation, and Perpetuation), the effects of sleep deprivation and disturbance on cognitive function, and the risks faced by shift workers and healthcare professionals from chronic sleep loss. The conversation also details the intricate relationship between our natural circadian rhythms, guided by light exposure, that are disrupted by many modern practices, and the potential for better aligning our biological clocks with nature through innovative tools and routines.

Ben and Prerna also discuss sleep chronotypes - night owls and morning larks - busting myths around later sleepers being lazier and whether society may benefit from observing these patterns. Without prescription, Prerna shares how consistency in sleep can lead to better health outcomes and how technology can both hinder and enhance our sleep health.

Dr Prerna Varma, PhD, is a Psychology Research Fellow in the School of Psychological Sciences at the Turner Institute for Brain and Mental Health in Australia. Prerna is deeply committed to examining as well as addressing sleep and mental health in underserved populations, including caregivers, people living with dementia, culturally diverse and other minoritised communities. She engages in and advocates for increasing public health awareness with the intent to improve sleep outcomes in our communities.

Find Prerna:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056503/

Studies mentioned or related to this episode:

Sleep regularity and mortality: https://doi.org/10.1093/sleep/zsad253 ; https://www.nature.com/articles/s41598-018-32402-5 ; https://www.medrxiv.org/content/10.1101/2023.09.08.23295231v1.full.pdf

Insomnia and stress during COVID: https://doi.org/10.1080/15402002.2022.2074996

Initial Testing of SleepSync app with shift workers: https://journals.sagepub.com/doi/pdf/10.1177/20552076231165972

Sleep and relationship conflicts: https://journals.sagepub.com/doi/abs/10.1177/1948550613488952 ; https://doi.org/10.1097%2FPSY.0b013e3181ecd08a ;

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Fatty Acid Research Institute

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Dr Bill Harris, PhD | Omega-3 - Healthspan's Best Friend

Wed, 08 May 2024 05:00:27 GMT

New to Omega-3 Fatty Acids? If you don’t know what fatty acids are or what they do for our health, there is no one better to learn from than Dr Harris on the topic. Ranked among the top 2% of scientists worldwide based on the impact of his research, Dr. Bill Harris has been a leading researcher in omega-3 fatty acids for over 40 years.

“If you care what your cholesterol level is, you better care what your omega 3 is because it’s more important than cholesterol in terms of telling you about your risk for heart disease”. Here with Ben, Dr Harris unveils how these essential nutrients, found predominantly in marine sources like EPA and DHA, are vital for reducing risks associated with major health issues such as heart disease, stroke, cognitive decline, and premature death.

Dr Bill Harris has over 300 scientific papers on fatty acids and health, the vast majority on omega-3. He has been on the faculty of three medical schools (Universities of Kansas, Missouri (at Kansas City), and South Dakota), and has received 5 NIH grants to study omega-3. He was the co-author on three AHA statements on fatty acids and heart health. As the co-inventor of the Omega-3 Index (and other omega-3 blood tests) and founder of OmegaQuant Analytics.

Find Dr Bill Harris and learn more:

Omegaquant Test - order a dry blood spot test to measure your omega-3 levels

Studies mentioned or related to this episode:

The Effects of Omega-3 Fatty Acid Supplementation on the Lipid Profile and Cardiovascular Markers Following Downhill Running in Long-Distance Runners

Plasma BDNF is a more reliable biomarker than erythrocyte omega-3 index for the omega-3 fatty acid enrichment of brain

Can omega-3 fatty acids help protect against hearing loss?

Assessing the Efficacy of Omega-3 Fatty Acids + Statins vs. Statins Only on Cardiovascular Outcomes

Estimation and predictors of the Omega-3 Index in the UK Biobank

Omega-3 Fatty Acids Improve Functionality of High-Density Lipoprotein in Individuals With High Cardiovascular Risk

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Dr Norm Dawson | Hearing Loss: A Modifiable Risk Factor of Dementia

Wed, 01 May 2024 05:00:43 GMT

At age 76, Dr Norm Dawson has been deaf for over 50 years and unlike many of his peers, he has no signs of dementia. Dr Norm sheds light on what he sees as a crucial but often overlooked aspect of cognitive function as we age: the profound connection between hearing loss and dementia.

Here, Ben and Dr Norm explore the Lancet Commission's 2020 findings on Dementia Prevention, Intervention and Care - covering 12 modifiable risk factors for dementia - a conversation gaining considerable momentum in brain health research. Dr Norm has a malleable view on health, and he emphasises the importance of taking personal responsibility for our well-being. As a passionate advocate for proactive health measures and thriving in adversity, he highlights the pivotal role of treating hearing impairment as soon as possible to reduce and delay further cognitive decline.

*For those listening, Dr norm explains how the cochlea implant works - to see the demonstration, head over to YouTube to watch!

Mentioned in this podcast:

Lancet Report 2020

Lisa Genova TED Talk - What You Can Do To Prevent Alzheimers

Find Dr Norm:

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Research Gate Publications

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Dr Ed Laskowski, M.D. | Momentum in Motion: Consistent and Quality Movement

Wed, 24 Apr 2024 05:00:46 GMT

A refreshing take on what it means to be ‘physically active’. It’s actually way more simple than sweating bullets in lycra, and Dr Ed Laskowski emphasises the enjoyment to be found in movement far beyond the gym and cliquey exercise niches. Dr. Laskowski navigates the complexities of modern living, urging us to prioritise consistency and quality in our movement practices.

We discuss:

-the power of strength training (mitigating muscle loss and enhancing joint function, vital for preventing falls and maintaining independence as we age)

-the importance of foundational movement and proper technique,

-the kinetic chain of movement and the triad of fitness: heart health, strength, and flexibility, with the added dimension of stability.

As Dr. Laskowski aptly puts it, why wait for a health crisis to make positive changes? Embracing movement as a preventative 'pill' enables us to maintain our ability to engage in the activities we love, for longer. So what are we waiting for?

Dr. Laskowski, MD, is a highly acclaimed figure in his field, and it’s not hard to see why. Dr Laskowski’s relatable persona and ability to succinctly filter the science in a way that is digestible may indeed be why he served Presidents Bush and Obama after being appointed to the President's Council on Physical Fitness and Sports. Dr Laskowski has been named among Americas Top Physicians, has served as an Olympic Polyclinic physician, in addition to publishing several hundred papers on health and fitness. He is also a former co-director of Mayo Clinic Sports Medicine (you may recognise this site from when you google your symptoms online).

Find Dr Ed Laskowski:

Twitter

MayoClinic.org - Strength Training Videos mentioned in this episode

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Dr Nathan Bryan, PhD | Nitric Oxide: The Foundation for Optimal Health

Wed, 17 Apr 2024 05:00:02 GMT

Ever heard of Nitric Oxide (NO)? We wonder why this molecule is so under-discussed as its profound role in our bodies suggests it should be top of the list. This simple molecule:

-controls oxygen and nutrient delivery to every cell in the body

-regulates cellular communication

-has anti-microbial properties that protect our body from invading pathogens.

The loss of nitric oxide production is recognised as the earliest event in the onset and progression of most if not all chronic diseases.

Dr Nathan Bryan is an international leader in molecular medicine and nitric oxide biochemistry - he has been at the fore of this field for two decades. In this episode, we explore the profound impact of nitric oxide (NO) deficiency on our health - from erectile dysfunction to cardiovascular disease, cognitive decline to sleep disorders, listen to the far-reaching consequences of inadequate NO production. But it's not all doom and gloom - Dr Nathan and Ben discuss with equal weight the pivotal role our choices make in the production of this molecule and where we produce it in the body - all helping you establish the crucial link between NO levels and overall well-being. Dr Nathan gives us simple things to be aware of that can optimise NO production and our enhance vascular, respiratory, and metabolic health. This episode gets pretty science-heavy at times, but stick with it and we can promise there's a lot to learn from Dr Nathan's extensive knowledge in this field!

Find Dr Nathan (Dr Nitric):

Book - Coming Soon!

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Dr Tom Walters, DPT, OCS | Mastering Movement: Pain, Rehab and Prehab

Wed, 03 Apr 2024 06:49:29 GMT

Dr. Tom Walters is a board-certified orthopaedic physical therapist who specialises in the treatment of pain and movement disorders. He is the founder of Rehab Science and dedicates his time to teaching people about human movement, pain, and how to most effectively recover from injury.

Tom runs one of the world’s largest social media accounts dedicated to physical rehab that helps over a million people to master their movement. He makes understanding pain and injury easy, simplifying the science, and then providing the best exercises and suggestions to start, improve and make a holistic recovery. His book (Rehab Science) covers the most common musculoskeletal conditions that many of us either currently have or will have in our lifetime - this episode and Tom's book may just save you a ton on physio appointments. Regardless of where you’re at now, the knowledge Tom shares is beneficial for any and all of us to take on board - for injury recovery and injury prevention in all domains.

In this episode, Tom and Ben discuss why we experience pain and the 3 types of pain, the difference between pain and injury, the cycle of pain avoidance, rehab vs. prehab, having a why behind movement habits, the importance of addressing impairments quickly and having a malleable mindset. As a source of knowledge on exercise, movement and the body - Dr Tom is the head-liner of the rehab science world and this is one to watch if you've ever suffered with any pain that debilitates you and lessens your ability to do the things you love.

Besides running his clinical practice, Tom served as a full-time undergraduate kinesiology professor for eight years where he taught human biomechanics, therapeutic exercise, and pain science. Tom received his bachelor’s degree in exercise science from Montana State University and his Doctor of Physical Therapy (DPT) degree from Chapman University. Afterwards, he completed a residency in orthopaedic manual physical therapy (OMPT) and a fellowship in lower quarter functional biomechanics.

Find Tom (Rehab Science):

Rehab Science - The Book

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The Blue Tits - Nippy Dippers

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Sian Richardson | Embracing the Chill - Finding Belonging, Community and Courage

Wed, 27 Mar 2024 06:00:41 GMT

We dive into the invigorating world of cold water immersion and the transformative power of community with Sian Richardson, founder of the Blue Tits Chill Dippers Community. In this episode, Sian shares her journey of building a global community of over 120,000 cold water enthusiasts, united by their love for the icy plunge and the warmth of camaraderie 🤝🏻

Sian illuminates the importance of embracing discomfort, confronting fear, and taking action in the face of uncertainty. From our innate human desire to belong, to the liberating effect of stopping overthinking, this episode is a conversation inspiring us to seize each moment, one small victory at a time. Discover the profound impact of simply showing up, spending time without an agenda, and the resilience gained from embracing failure. With heartfelt anecdotes and practical insights, Sian will empower you to challenge your limits, cultivate courage, and find solace in a community.

We hope you enjoy this conversation as much as we did. If you choose to move through overthinking even with fear and try something new because of it - let us know on our instagram page! We’d love to hear from you.

Find your local dipping community:

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Autumn COVID‑19 surge dates in Europe correlated to latitudes, not to temperature‑humidity, pointing to vitamin D as contributing factor

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Dr Roger Seheult, M.D. | Part 2 | Light as Medicine - Red Light, Infrared and Long COVID

Wed, 20 Mar 2024 06:00:41 GMT

This is Part 2 of our conversation with Dr Roger Seheult. We highly recommend listening to Part 1 as a precursor to this episode to get the most out of terms and topics covered!

In this episode, we discuss:

-emerging research around red light and infra-red light

-the impact of sunlight on Covid-19 surges

-long covid

-tools that may not only support in recovery from long covid, but could possibly speed up the rate at which you recover from other illnesses in the future too

Recap of Part 1:

-the light spectrum of UV to infra-red

-the importance of light exposure to regulate our circadian rhythm and reduce oxidative stress

-impacts of light on hypersomnia, sleep inertia, hunger and satiety cues

-the best times of day to eat, and differences in our insulin sensitivity

A recap on Dr. Seheult - Roger is quadruple board-certified in Internal Medicine, Pulmonary Diseases, Critical Care Medicine, and Sleep Medicine through the American Board of Internal Medicine. He has a practice in California where he is a critical care physician, pulmonologist, and sleep physician. He lectures across the country, is the director of a sleep lab, and is the Medical Director for a Respiratory Care Program. In 2012 he co founded MedCram, a medical education company with videos that support medical learning (and over 1.5 million YouTube Subscribers).

His passion is "demystifying" medical concepts.

Find Dr Roger's work:

MedCram Website

MedCram YouTube

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Studies mentioned in Part 1 and 2:

Ultraviolet A radiation and COVID-19 deaths in the USA with replication studies in England and Italy

A geographical approach to the development of hypotheses relating to Covid-19 death rates

Cardiopulmonary and hematological effects of infrared LED photobiomodulation in the treatment of SARS-COV2

Insufficient Sun Exposure Has Become a Real Public Health Problem

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Autumn COVID‑19 surge dates in Europe correlated to latitudes, not to temperature‑humidity, pointing to vitamin D as contributing factor

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Dr Roger Seheult, M.D. | Part 1 | Light as Medicine - Light Exposure on Circadian Rhythm, Sleep and Metabolic Function

Thu, 14 Mar 2024 06:00:23 GMT

In Part 1 of this episode about light as medicine, Dr Roger Seheult talks us through the light spectrum of UV to infra-red and the importance of exposure to types of light at certain times of the day to regulate our circadian rhythm. Many of us suffer from some form of circadian rhythm dysfunction due to the technology-driven societies we live in. As a result, the cues our body takes from the external environment can become out of sync with our internal environment, causing an imbalance in many of our basic functions - the processes that aid good quality sleep, metabolic function, and everything down stream of these. We also discuss the impacts of light on hypersomnia, sleep inertia, hunger and satiety cues, the best times of day to eat, insulin sensitivity, infra red light and oxidative stress.

Dr. Seheult is currently an Associate Clinical Professor at the University of California and an Assistant Clinical Professor at the School of Medicine and Allied Health at Loma Linda University. Dr. Roger is quadruple board-certified in Internal Medicine, Pulmonary Diseases, Critical Care Medicine, and Sleep Medicine. In 2012, he and Kyle Allred founded MedCram, a medical education company that creates videos utilised by hospitals, medical schools, and hundreds of thousands of medical professionals from all over the world (and over 1.5 million YouTube Subscribers).

His passion is "demystifying" medical concepts.

Tune in next week for Part 2 for more on the emerging research around red light, infra-red light, the impact of sunlight on Covid-19 surges, long covid, and possible tools to support in recovery from long covid.

Find Dr Roger's work:

MedCram Website

MedCram YouTube

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Studies mentioned in this podcast:

Ultraviolet A radiation and COVID-19 deaths in the USA with replication studies in England and Italy

A geographical approach to the development of hypotheses relating to Covid-19 death rates

Cardiopulmonary and hematological effects of infrared LED photobiomodulation in the treatment of SARS-COV2

Insufficient Sun Exposure Has Become a Real Public Health Problem

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Want to watch this on video? Subscribe on YouTube

Instagram @degreesofhealth

Tik Tok @degrees_of_health

Cardiovascular and Other Health Benefits of Sauna Bathing: A Review of the Evidence

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Julien Périard | Heat Stress and Performance

Wed, 21 Feb 2024 06:00:43 GMT

Julien Périard is a research professor and deputy director of the University of Canberra Research Institute for Sport and Exercise. In our conversation, Julien proved to be a hub of information regarding heat stress, having worked with amateur and professional athletes across various sporting disciplines, and also with National and International Federations like World Triathlon and FIFA.

In this episode, we discuss heat stress - what is it? Heat for recovery and heat for performance, VO2 max, pre cooling before exercise, perceived exertion, hydration, the placebo effect, and more. Julien gives detailed scientific explanations on how, what and why aspects of heat are measured in the lab, but also speaks to the inferences we can take from these in the challenges we face in light of our warming climate.

Currently, Julien is working on developing extreme heat policies for safely exercising in hot environmental conditions and using exercise and heat exposure to maintain or improve resilience to rising global temperatures.

Find Julien:

University of Canberra

Twitter

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Studies mentioned in this podcast:

Standalone sauna vs exercise followed by sauna on cardiovascular function in non-naïve sauna users: A comparison of acute effects

Effects of physical exercise and cold stimulation on serum testosterone level in men

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The Breathe with Níall Podcast

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Níall Ó'Murchú | The Blissful Breath and The Power of the Cold

Wed, 14 Feb 2024 06:00:09 GMT

Breath work instructor, wellness expert of 22 years, and author Níall Ó’Murchú grew up going in and out of the waters around County Dublin. What moved from childhood play and curiosity, has burgeoned into a practice, a philosophy, and a lifestyle for Níall, his family, and all those lucky enough to be taught by him.

We talk about the importance of setting intentions going into the cold, and how this shapes our experience each time, the cold as a respite from grief, tightness, struggle, the art of ‘letting go’ and surrendering to soften, and bringing our physicalities (tension, breath, mood, state) conscious.

There could be several reasons you are interested in entertaining some cold in your life - physical health, easing pain or inflammation, performance, recovery, or perhaps there’s just a dose of curiosity getting the better of you. The wonderful thing with the cold is that whatever your reason to start, it may not what you’ll end up finding. And Níall explains how the same could be said for breath work. But the most powerful tool? Bringing them together. There’s no way of foretelling what you might find beyond that.

Like anything worth having, what we do know is the more regular the practice, the deeper it can seep - this merciless teacher of the cold and the power of the breath can help us find ultimate calm amidst any chaos.

Find Níall:

Níall's books:

The Blissful Breath

The Power of Cold

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Mentioned in this podcast:

Choke documentary - Rickson Gracie

Studies mentioned in this podcast:

The positive effects of combined breathing techniques and cold exposure on perceived stress: a randomised trial

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Maximal sustained energy budgets in humans and animals

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Dr Cara Ocobock, PhD | Humans at Extremes: Biological Underpinnings of our Evolution

Wed, 31 Jan 2024 06:00:46 GMT

To understand our physiology and health today, it’s critical to look back - a long way - at our evolution, not only to inform our now, but to better understand which mechanisms we may need to sustain us in the face of our changing world. Dr Cara Ocobock is an evolutionary anthropology encyclopaedia, an enthusiastic academic, and an incredibly engaging listen.

In this episode, Dr Cara helps us to understand some of the interactions between our physiology, our evolution and our environments. In Cara’s work with reindeer herders in Finland, she explores physiological and behavioural mechanisms required to cope and adapt to extreme climates and activity. We discuss her findings into brown adipose tissue (BAT or brown fat), metabolic health, male/female differences, the potential drivers of metabolically healthy obesity, and the role of oestrogen in the body (spoiler: gents - you need this too!)

Find Cara:

cocobock@nd.edu

‘Cara Ocobock’ Twitter, Bluesky, Threads

Cara also has a podcast of her own disseminating innovative research in the field - Sausage of Science

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Mentioned in this podcast:

Jeremy DeSilva

Milford Wolpuff

Herman Pontzer

University of Lapland

University of Oulu

Studies mentioned in this podcast:

Commentary - fat but fit…and cold?

More of Cara’s work:

Human Energy Expenditure in Anthropology and Beyond

Human Bodies in Extreme Environments

Human cold adaptation: An unfinished agenda v2.0

Brown adipose tissue thermogenesis among a small sample of reindeer herders from sub-Arctic Finland

Between a rock and a cold place: Neanderthal biocultural cold adaptations

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University of Portsmouth website

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Professor Mike Tipon MBE, MSc, PhD | Cold Water Immersion: Kill or Cure?

Wed, 24 Jan 2024 06:00:50 GMT

Head of the extreme environments lab at Portsmouth University, Professor Mike Tipton MBE has spent his working life understanding, evaluating and enhancing the comfort, performance and survival of human beings in extreme environments. With decades of knowledge gained in the lab, the aim is to apply the science to areas where it has most use and benefit. Having worked with the likes of the Ministry of Defence, RNLI and Olympic and Paralympic athletes, Mike is well-positioned to speak to the scientific and practical sides of the human response to cold water immersion.

Critically, he clarifies what we don’t yet know, and what we need to be aware of in the time frame between now and finding out. We discuss what happens and why, the benefits and risks of both unintentional and intentional immersion, common mistakes about cold water, what he calls ‘the thermostatic human’, and ultimately, his faith in the resilience of human beings.

Anglers, coastal walkers, yacht sailors, dinghy sailors, kayakers, open water or wild swimmers - pretty much anyone who operates or interacts by, under, or on the sea - there is an ocean of critical information to learn in this episode. It is applied science at the top of its game.

Find Mike:

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Mentioned in this podcast:

Non-freezing cold injury

Cold shock response

Mammalian dive reflex

Autonomic conflict

Lewis Pugh

Studies mentioned in this podcast:

Humans: A homeothermic animal that needs perturbation

Cold water immersion: kill or cure?

Cold water therapies - minimising risks

Moving in extreme environments: open water swimming in cold and warm water

Open water swimming as a treatment for major depressive disorder

Drifting into unconsciousness: Jason Zirganos and the mystery of undetected hypothermia

Human Brown Adipose Tissue—A Decade Later

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Dean Hall | How Cold Water Cured my Cancer

Wed, 17 Jan 2024 06:00:11 GMT

Dean Hall went from working 100 hour weeks as a licensed therapist and coach, to receiving a 2-6 week diagnosis to live. Our conversation with Dean documents his 11 year old dream to swim the English Channel, turned realised adult and active-cancer patient achievement of swimming the 187 miles of the cold Willamette River in Oregon. All this through a leukaemia diagnosis, a lymphoma diagnosis, bouts of pneumonia and viral meningitis, and the grief of losing his wife. Inspired to see through raising his then 14-year old daughter, he committed to do anything to prolong his time to fulfil that role. This is the story of The Wild Cure - on the critical power of finding a passionate purpose and how cold water swimming and nature led him to heal his cancer and traumatic grief.

With Dean we discuss his radical remission, the power of visualisation, how we can let go of overwhelming emotions of the day via a process of ‘zero-ing out’, and the symbiotic relationship we need to return to with nature.

Find Dean: